Trial · NCT04177654
Monitoring Drug Efficacy and Anthelmintic Resistance in Soil-transmitted Helminth Programs
NCT04177654, Completed, University Ghent
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Monitoring Drug Efficacy and Anthelmintic Resistance in Soil-transmitted Helminth Programs. Trials, record NCT04177654. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04177654
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Monitoring Drug Efficacy and Anthelmintic Resistance in Soil-transmitted Helminth Programs
- NCT number
- NCT04177654
- Status
- Completed
- Enrollment
- 9,457 participants, actual
- Lead sponsor
- University Ghent
- Conditions
- Soil-transmitted Helminth Infections
- Interventions
- Benzimidazoles
- First posted
- 2019-11-26
- Last updated
- 2023-08-29
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | moderate/heavy intensity infections of the different STH | up to 12 months | The data collected at baseline (prior to treatment) will provide valuable information on the infection intensities and prevalence of the different STH in that population. |
| Primary | drug efficacy of a single dose of BZ drugs against STH infections in these countries | up to 12 months | The reduction in egg output of the cohort of infected school aged children will inform us on the efficacy of the administered drug. |
| Primary | frequency of the ß-tubulin SNPs linked to BZ resistance | up to 12 months | The collected stool samples will be analyzed and SNPs linked to benzimidazole drug resistance in STH will be quantified using molucular techniques like pyrosequencing, whole gene sequencing and LAMP. |
| Secondary | costs related to monitoring drug efficacy and AR in national PC programs for STH. | up to 12 months | The absolute cost of the different drug efficacy studies will be evaluated using a standardized cost-description protocol to help provide a general estimate of the cost of implementing routine drug efficacy studies in endemic areas. |
| Secondary | Expand the Starworms repository of STH field samples | up to 12 months | The collection of stool samples will provide a valuable addition to the Starworms repository of STH field samples which can serve other research. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04177654
GET https://conductscience.org/api/trials/v1/NCT04177654/registered