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Trial · NCT04194944

Results by group40

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Progression Free Survival (PFS) by Blinded Independent Central Review (BICR) (With Pembrolizumab)Selpercatinib (TRT A)24.8495% Confidence Interval 16.89 to NAMonths
Progression Free Survival (PFS) by Blinded Independent Central Review (BICR) (With Pembrolizumab)Pemetrexed and Platinum With Pembrolizumab (TRT B)11.1795% Confidence Interval 8.77 to 16.76Months
PFS by BICR (With or Without Pembrolizumab)Selpercatinib (TRT A)24.8495% Confidence Interval 17.31 to NAMonths
PFS by BICR (With or Without Pembrolizumab)Pemetrexed and Platinum With or Without Pembrolizumab (TRT B)11.1795% Confidence Interval 8.77 to 16.76Months
Percentage of Participant With Disease Control Rate (DCR) by BICR (With Pembrolizumab)Selpercatinib (TRT A)89.195% Confidence Interval 82.5 to 93.9Percentage of Participants
Percentage of Participant With Disease Control Rate (DCR) by BICR (With Pembrolizumab)Pemetrexed and Platinum With Pembrolizumab (TRT B)84.395% Confidence Interval 74.7 to 91.4Percentage of Participants
Percentage of Participant With DCR by BICR (With or Without Pembrolizumab)Selpercatinib (TRT A)89.395% Confidence Interval 83.4 to 93.7Percentage of Participants
Percentage of Participant With DCR by BICR (With or Without Pembrolizumab)Pemetrexed and Platinum With or Without Pembrolizumab (TRT B)82.495% Confidence Interval 73.6 to 89.2Percentage of Participants
PFS2 (With Pembrolizumab)Selpercatinib (TRT A)NA95% Confidence Interval NA to NAMonths
PFS2 (With Pembrolizumab)Pemetrexed and Platinum With Pembrolizumab (TRT B)NA95% Confidence Interval NA to NAMonths
PFS2 (With or Without Pembrolizumab)Selpercatinib (TRT A)NA95% Confidence Interval NA to NAMonths
PFS2 (With or Without Pembrolizumab)Pemetrexed and Platinum With or Without Pembrolizumab (TRT B)NA95% Confidence Interval NA to NAMonths
Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) by BICR (With Pembrolizumab)Selpercatinib (TRT A)83.795% Confidence Interval 76.2 to 89.6Percentage of participants
Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) by BICR (With Pembrolizumab)Pemetrexed and Platinum With Pembrolizumab (TRT B)65.195% Confidence Interval 53.8 to 75.2Percentage of participants
ORR: Percentage of Participants With CR or PR by BICR (With or Without Pembrolizumab)Selpercatinib (TRT A)83.695% Confidence Interval 77.0 to 89.0Percentage of Participants
ORR: Percentage of Participants With CR or PR by BICR (With or Without Pembrolizumab)Pemetrexed and Platinum With or Without Pembrolizumab (TRT B)62.795% Confidence Interval 52.6 to 72.1Percentage of Participants
Duration of Response (DoR) by BICR (With Pembrolizumab)Selpercatinib (TRT A)24.1895% Confidence Interval 17.94 to NAMonths
Duration of Response (DoR) by BICR (With Pembrolizumab)Pemetrexed and Platinum With Pembrolizumab (TRT B)11.4795% Confidence Interval 9.66 to 23.26Months
DOR by BICR (With or Without Pembrolizumab)Selpercatinib (TRT A)24.1895% Confidence Interval 17.94 to NAMonths
DOR by BICR (With or Without Pembrolizumab)Pemetrexed and Platinum With or Without Pembrolizumab (TRT B)11.9995% Confidence Interval 9.69 to 23.26Months

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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