Trial · NCT04204798

Dexmedetomidine and Outcomes of Elderly Admitted to ICU After Surgery

NCT04204798, Not applicable, Active not recruiting, Peking University First Hospital

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Dexmedetomidine and Outcomes of Elderly Admitted to ICU After Surgery. Trials, record NCT04204798. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04204798

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Dexmedetomidine and Outcomes of Elderly Admitted to ICU After Surgery
NCT number: NCT04204798
Status: Active not recruiting
Phases: Not applicable
Enrollment: 1,410 participants, actual
Lead sponsor: Peking University First Hospital
Conditions: Elderly, Surgery, Intensive Care Unit, Dexmedetomidine, Overall Survival
Interventions: Dexmedetomidine, Placebo
First posted: 2019-12-19
Last updated: 2025-07-31

Source ClinicalTrials.gov

Registered outcomes17

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Overall survival after surgery	Up to 4 years after surgery	Overall survival after surgery
Secondary	The incidence of organ injury within 5 days after surgery	Up to 5 days after surgery	Organ injury include delirium (assessed with Confusion Assessment Method/CAM for the Intensive Care Unit), acute kidney injury (assessed with KIDGO criteria), and myocardial injury (assessed with cardiac troponin I).
Secondary	Length of stay in the intensive care unit (ICU) stay after surgery	Up to 30 days after surgery	Length of ICU stay after surgery
Secondary	Length of stay in hospital after surgery	Up to 30 days after surgery	Length of stay in hospital after surgery
Secondary	Incidence of postoperative complications within 30 days after surgery	Up to 30 days after surgery	Postoperative complications are defined as newly occured medical events that are harmful to patients' recovery and required interventional therapy.
Secondary	Rate of all-cause 30-day mortality after surgery	Up to 30 days after surgery	All-cause 30-day mortality after surgery
Secondary	Sleep quality at 30 days after surgery	At 30 days after surgery	The sleep quality is assessed with the Pittsburgh Sleep Quality Index Questionnaire (PSQI, score ranges from 0 to 21, with higher score indicating poorer sleep quality).
Secondary	Recurrence-free survival after surgery	Up to 4 year after surgery	Recurrence-free survival after surgery
Secondary	Event-free survival after surgery	Up to 4 year after surgery	Event-free survival after surgery
Secondary	Cancer-specific survival after surgery	Up to 4 year after surgery	Cancer-specific survival after surgery

1 to 10 of 17Source ClinicalTrials.gov

See all 17 registered outcomes

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers46

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as	Source
2360740	BACKGROUND	PubMed
3921096	BACKGROUND	PubMed
8957969	BACKGROUND	PubMed
10470711	BACKGROUND	PubMed
10660851	BACKGROUND	PubMed
10713011	BACKGROUND	PubMed
11161124	BACKGROUND	PubMed
11179121	BACKGROUND	PubMed
11373507	BACKGROUND	PubMed
11797025	BACKGROUND	PubMed

1 to 10 of 46

See all 46 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04204798

GET https://conductscience.org/api/trials/v1/NCT04204798/papers?page=2

API reference For AI assistants