Trial · NCT04218084
Results by group46
Each measurement the trial posted, group by group, in the words and numbers it posted.
1 to 20 of 46
Download this page as JSON| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change From Baseline in Time-Averaged Maximum of Mean Velocity (TAMMV) Arterial Cerebral Blood Flow at Week 24 | Voxelotor | -12.06 | 95% Confidence Interval -15.82 to -8.31 | cm/sec | |
| Change From Baseline in Time-Averaged Maximum of Mean Velocity (TAMMV) Arterial Cerebral Blood Flow at Week 24 | Placebo | -4.29 | 95% Confidence Interval -8.17 to -0.40 | cm/sec | |
| Change From Baseline in TAMMV Arterial Cerebral Blood Flow at Week 48 | Voxelotor | -10.33 | 95% Confidence Interval -14.14 to -6.52 | cm/sec | |
| Change From Baseline in TAMMV Arterial Cerebral Blood Flow at Week 48 | Placebo | -3.86 | 95% Confidence Interval -7.77 to 0.05 | cm/sec | |
| Time to Conversion to Abnormal TCD Flow | Voxelotor | NA | 95% Confidence Interval NA to NA | Weeks | |
| Time to Conversion to Abnormal TCD Flow | Placebo | NA | 95% Confidence Interval NA to NA | Weeks | |
| Time to Reversion to Normal TCD Flow | Voxelotor | 9.3 | Full Range 7 to 73 | Weeks | |
| Time to Reversion to Normal TCD Flow | Placebo | 17.0 | Full Range 8 to 96 | Weeks | |
| Percentage of Participants With TAMMV Reduced by >=15 cm/Sec From Baseline at Weeks 24, 48 and 96 | Voxelotor | Week 24 | 38.3 | Percentage of participants | |
| Percentage of Participants With TAMMV Reduced by >=15 cm/Sec From Baseline at Weeks 24, 48 and 96 | Placebo | Week 24 | 25.9 | Percentage of participants | |
| Percentage of Participants With TAMMV Reduced by >=15 cm/Sec From Baseline at Weeks 24, 48 and 96 | Voxelotor | Week 48 | 39.2 | Percentage of participants | |
| Percentage of Participants With TAMMV Reduced by >=15 cm/Sec From Baseline at Weeks 24, 48 and 96 | Placebo | Week 48 | 27.6 | Percentage of participants | |
| Percentage of Participants With TAMMV Reduced by >=15 cm/Sec From Baseline at Weeks 24, 48 and 96 | Voxelotor | Week 96 | 30.0 | Percentage of participants | |
| Percentage of Participants With TAMMV Reduced by >=15 cm/Sec From Baseline at Weeks 24, 48 and 96 | Placebo | Week 96 | 30.2 | Percentage of participants | |
| Change From Baseline in Hemoglobin (Hb) at Weeks 24, 48 and 96 | Voxelotor | Week 24 | 0.89 | 95% Confidence Interval 0.65 to 1.14 | Grams per deciliter (g/dL) |
| Change From Baseline in Hemoglobin (Hb) at Weeks 24, 48 and 96 | Placebo | Week 24 | 0.18 | 95% Confidence Interval -0.08 to 0.44 | Grams per deciliter (g/dL) |
| Change From Baseline in Hemoglobin (Hb) at Weeks 24, 48 and 96 | Voxelotor | Week 48 | 0.79 | 95% Confidence Interval 0.54 to 1.04 | Grams per deciliter (g/dL) |
| Change From Baseline in Hemoglobin (Hb) at Weeks 24, 48 and 96 | Placebo | Week 48 | -0.19 | 95% Confidence Interval -0.45 to 0.07 | Grams per deciliter (g/dL) |
| Change From Baseline in Hemoglobin (Hb) at Weeks 24, 48 and 96 | Voxelotor | Week 96 | 0.08 | 95% Confidence Interval -0.20 to 0.35 | Grams per deciliter (g/dL) |
| Change From Baseline in Hemoglobin (Hb) at Weeks 24, 48 and 96 | Placebo | Week 96 | -0.14 | 95% Confidence Interval -0.42 to 0.14 | Grams per deciliter (g/dL) |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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