Trial · NCT04230577
Photobiomodulation to Improve Cognition in TBI, With fMRI
NCT04230577, Early phase 1, Unknown, Boston VA Research Institute, Inc.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Photobiomodulation to Improve Cognition in TBI, With fMRI. Trials, record NCT04230577. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04230577
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Photobiomodulation to Improve Cognition in TBI, With fMRI
- NCT number
- NCT04230577
- Status
- Unknown
- Phases
- Early phase 1
- Enrollment
- 20 participants, estimated
- Lead sponsor
- Boston VA Research Institute, Inc.
- Conditions
- Traumatic Brain Injury, Closed Head Injury, Cognitive Dysfunction
- Interventions
- Real LED Intervention, Sham LED Intervention
- First posted
- 2020-01-18
- Last updated
- 2022-02-25
Source ClinicalTrials.gov
Registered outcomes92
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | CVLT-II, Long Delay Free Recall 1 | Change from Pre-Treatment Baseline to 1-Week after Series 1 | California Verbal Learning Test-II Long Delay (20 mins) Free Recall; Measures Verbal Memory Min score of 0 and a max score of 16; higher score = better outcome. After a 20 minute delay (other tasks run during this delay), participant is asked to recall items from List A. Total is number of words recalled. Alternate lists are used at each testing timepoint to avoid practice effect |
| Primary | CVLT-II, Long Delay Free Recall 2 | Change from Pre-Treatment Baseline to 1-Month after Series 1 | California Verbal Learning Test-II Long Delay (20 mins) Free Recall; Measures Verbal Memory Min score of 0 and a max score of 16; higher score = better outcome. After a 20 minute delay (other tasks run during this delay), participant is asked to recall items from List A. Total is number of words recalled. Alternate lists are used at each testing timepoint to avoid practice effect |
| Primary | CVLT-II, Long Delay Free Recall 3 | Change from 1-Week to 1-Month after Series 1 | California Verbal Learning Test-II Long Delay (20 mins) Free Recall; Measures Verbal Memory Min score of 0 and a max score of 16; higher score = better outcome. After a 20 minute delay (other tasks run during this delay), participant is asked to recall items from List A. Total is number of words recalled. Alternate lists are used at each testing timepoint to avoid practice effect |
| Primary | CVLT-II, Long Delay Free Recall 4 | Change from Pre-Treatment Baseline to 1-Week after Series 2 | California Verbal Learning Test-II Long Delay (20 mins) Free Recall; Measures Verbal Memory Min score of 0 and a max score of 16; higher score = better outcome. After a 20 minute delay (other tasks run during this delay), participant is asked to recall items from List A. Total is number of words recalled. Alternate lists are used at each testing timepoint to avoid practice effect |
| Secondary | CVLT-II, Short Delay Free Recall 1 | Change from Pre-Treatment Baseline to 1-Week after Series 1 | California Verbal Learning Test-II Immediate Free Recall; Measures Verbal Memory Min score of 0 and a max score of 16; higher score = better outcome Participant is asked to recall items from List A. Total is number of words recalled. |
| Secondary | CVLT-II, Short Delay Free Recall 2 | Change from Pre-Treatment Baseline to 1-Month after Series 1 | California Verbal Learning Test-II Immediate Free Recall; Measures Verbal Memory Min score of 0 and a max score of 16; higher score = better outcome Participant is asked to recall items from List A. Total is number of words recalled. |
| Secondary | CVLT-II, Short Delay Free Recall 3 | Change from 1-Week to 1-Month after Series 1 | California Verbal Learning Test-II Immediate Free Recall; Measures Verbal Memory Min score of 0 and a max score of 16; higher score = better outcome Participant is asked to recall items from List A. Total is number of words recalled. |
| Secondary | CVLT-II, Short Delay Free Recall 4 | Change from Pre-Treatment Baseline to 1-Week after Series 2 | California Verbal Learning Test-II Immediate Free Recall; Measures Verbal Memory Min score of 0 and a max score of 16; higher score = better outcome Participant is asked to recall items from List A. Total is number of words recalled. |
| Secondary | CVLT-II, Short Delay Cued Recall 1 | Change from Pre-Treatment Baseline to 1-Week after Series 1 | California Verbal Learning Test-II Immediate Cued Recall; Measures Verbal Memory Participants are asked to immediately recall items from a list, but are given cues by category. (4 categories, 4 items each). Total is score across all 4 categories. |
| Secondary | CVLT-II, Short Delay Cued Recall 2 | Change from Pre-Treatment Baseline to 1-Month after Series 1 | California Verbal Learning Test-II Immediate Cued Recall; Measures Verbal Memory Participants are asked to immediately recall items from a list, but are given cues by category. (4 categories, 4 items each). Total is score across all 4 categories. |
1 to 10 of 92Source ClinicalTrials.gov
See all 92 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Verbal Learning | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04230577
GET https://conductscience.org/api/trials/v1/NCT04230577/registered?page=2