Trial · NCT04234191
Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder
NCT04234191, Phase 2, Unknown, University of British Columbia
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder. Trials, record NCT04234191. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04234191
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder
- NCT number
- NCT04234191
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 50 participants, estimated
- Lead sponsor
- University of British Columbia
- Conditions
- Opioid Use Disorder
- Interventions
- Buprenorphine/naloxone, Hydromorphone
- First posted
- 2020-01-21
- Last updated
- 2024-06-11
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Successful induction of bup/nx with low levels of withdrawal | Baseline to Day 1 (Standard Induction Arm) or Day 2 (Rapid Micro-Induction Arm) | This is defined as the following: participants who remain in treatment until they have received a total daily dose of ≥ 8mg of bup/nx (successful induction), and score ≤ 12 on the COWS (low levels of withdrawal) from baseline to when they reach that dose. |
| Secondary | Illicit drug use | Baseline to Day 1 (Standard Induction Arm) or Day 2 (Rapid Micro-Induction Arm) | Assessed by urine drug screens (UDS) and Treatment Outcomes Profile (TOP). |
| Secondary | Drug use behaviour | Baseline to Day 1 (Standard Induction Arm) or Day 2 (Rapid Micro-Induction Arm) | Assessed by the Treatment Outcomes Profile (TOP). |
| Secondary | Treatment retention | Day 7 | Participants who pick up their prescription of bup/nx on Day 7. Assessed via the pharmacy database. |
| Secondary | Craving | Baseline to Day 1 (Standard induction Arm) or Day 2 (Rapid Micro-Induction Arm) | Assessed by the numeric craving scale. |
| Secondary | Pain | Baseline to Day 1 (Standard induction Arm) or Day 2 (Rapid Micro-Induction Arm) | Assessed by the numeric pain scale. |
| Secondary | Physical health | Baseline (both arms) | Assessed by the health section of the Opiate Treatment Index (OTI). |
| Secondary | Client satisfaction | Day 1 (Standard induction Arm) or Day 2 (Rapid Micro-Induction Arm) | Assessed by the Treatment Perceptions Questionnaire (TPQ). |
| Secondary | Appearance of adverse events | Baseline to Day 1 (Standard induction Arm) or Day 2 (Rapid Micro-Induction Arm) | Assessed by an adverse events report form. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers6
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04234191
GET https://conductscience.org/api/trials/v1/NCT04234191/registered