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Trial · NCT04234568

Results by group21

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Maximum Tolerated Dose (MTD) of Triapine and Recommended Phase 2 Dose (RP2D)Escalation Phase150milligrams
Maximum Tolerated Dose (MTD) of Triapine and Recommended Phase 2 Dose (RP2D)Expansion Phase150milligrams
Dose Limiting Toxicity (DLT)Escalation Phase Dose Level 1 (100mg Triapine)Grade 4 Neutropenia0participants
Dose Limiting Toxicity (DLT)Escalation Phase Dose Level 2 (150mg Triapine)Grade 4 Neutropenia2participants
Dose Limiting Toxicity (DLT)Escalation Phase Dose Level 3 (200mg Triapine)Grade 4 Neutropenia0participants
Dose Limiting Toxicity (DLT)Expansion Phase Dose Level 1 (100mg Triapine)Grade 4 Neutropenia0participants
Dose Limiting Toxicity (DLT)Expansion Phase Dose Level 2 (150mg Triapine)Grade 4 Neutropenia5participants
Dose Limiting Toxicity (DLT)Escalation Phase Dose Level 1 (100mg Triapine)Grade 5 Cardiac Arrest0participants
Dose Limiting Toxicity (DLT)Escalation Phase Dose Level 2 (150mg Triapine)Grade 5 Cardiac Arrest0participants
Dose Limiting Toxicity (DLT)Escalation Phase Dose Level 3 (200mg Triapine)Grade 5 Cardiac Arrest1participants
Dose Limiting Toxicity (DLT)Expansion Phase Dose Level 1 (100mg Triapine)Grade 5 Cardiac Arrest0participants
Dose Limiting Toxicity (DLT)Expansion Phase Dose Level 2 (150mg Triapine)Grade 5 Cardiac Arrest0participants
Dose Limiting Toxicity (DLT)Escalation Phase Dose Level 1 (100mg Triapine)Grade 3 Anemia0participants
Dose Limiting Toxicity (DLT)Escalation Phase Dose Level 2 (150mg Triapine)Grade 3 Anemia0participants
Dose Limiting Toxicity (DLT)Escalation Phase Dose Level 3 (200mg Triapine)Grade 3 Anemia0participants
Dose Limiting Toxicity (DLT)Expansion Phase Dose Level 1 (100mg Triapine)Grade 3 Anemia1participants
Dose Limiting Toxicity (DLT)Expansion Phase Dose Level 2 (150mg Triapine)Grade 3 Anemia0participants
Overall Response Rate (ORR)Escalation Phase Dose Level 1 (100mg Triapine)33.3percentage of participants
Overall Response Rate (ORR)Escalation Phase Dose Level 2 (150mg Triapine)18.2percentage of participants
Overall Response Rate (ORR)Expansion Phase Dose Level 1 (100mg Triapine)0percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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