Trial · NCT04276727
Menthol In Neuropathy Trial
NCT04276727, Phase 2, Completed, University of Edinburgh
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Menthol In Neuropathy Trial. Trials, record NCT04276727. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04276727
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Menthol In Neuropathy Trial
- NCT number
- NCT04276727
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 52 participants, actual
- Lead sponsor
- University of Edinburgh
- Conditions
- Chemotherapy-induced Peripheral Neuropathy
- Interventions
- MINT study IMP
- First posted
- 2020-02-19
- Last updated
- 2022-09-14
Source ClinicalTrials.gov
Registered outcomes18
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Reduction in CIPN symptoms | 6 weeks | A clinically significant reduction in pain (at least a 30% decrease in total BPI SF score as relates to the index neuropathic pain) between baseline and 6 weeks. |
| Secondary | Treatment effect on Chemotherapy Induced Peripheral Neuropathy | 6 weeks | Changes in EORTC QLQ (European Organisation for Research and Treatment of Cancer Quality of Life Questionnaires) CIPN-20 (severity of 20 symptoms rated on 4 point scale from Not at all to Very much) |
| Secondary | Treatment effect on quality of life functions | 6 weeks | Changes in EORTC QLC-c30 scores (30 symptoms on same scale as CIPN) |
| Secondary | Treatment effect on pain scores | 6 weeks | Changes in Brief Pain Inventory - Short Form scores (13 symptoms rated from 0 None to 10 Worst) |
| Secondary | Treatment effect on anxiety and depression | 6 weeks (14 symptoms rated from 0 to 3 in severity) | Changes in Hospital Anxiety and Depression Scale (HADS) scores |
| Secondary | Treatment effect on pain catastrophisation | 6 weeks (13 questions rated from 0-4 in severity) | Changes in Pain Catastrophising Scale (PCS) scores |
| Secondary | Treatment effect on side effects | 6 weeks | Changes in side effects (Yes/No to any SEs, description of SE to be given) |
| Secondary | Treatment effect on physical activity | 6 weeks | Changes in Actigraph data (measures of step counts, amount of moderate/vigorous activity and sleep times/efficiency) |
| Secondary | Perceived effects of IMP | 6 weeks | Changes in perceived effects questions (How long participant thinks treatment takes to take effect and how long it lasts for) |
| Other | Changes in Functional Magnetic Imaging data | 6 weeks | Changes in FMRI data pre and post treatment |
1 to 10 of 18Source ClinicalTrials.gov
See all 18 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04276727
GET https://conductscience.org/api/trials/v1/NCT04276727/registered