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Trial · NCT04280081

Results by group38

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Primary Analysis Set: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by Independent Review Committee (IRC)RET Fusion Positive Non-small Cell Lung Cancer (NSCLC) Cohort 1Complete Response3.895% Confidence Interval 0.1 to 19.6percentage of participants
Primary Analysis Set: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by Independent Review Committee (IRC)RET Fusion Positive Thyroid Cancer (TC) Cohort 1Complete Response095% Confidence Interval 0.0 to 97.5percentage of participants
Primary Analysis Set: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by Independent Review Committee (IRC)RET Mutant Medullary Thyroid Cancer (MTC) Cohort 2Complete Response7.795% Confidence Interval 0.9 to 25.1percentage of participants
Primary Analysis Set: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by Independent Review Committee (IRC)RET Fusion Positive Non-small Cell Lung Cancer (NSCLC) Cohort 1Partial Response65.495% Confidence Interval 44.3 to 82.8percentage of participants
Primary Analysis Set: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by Independent Review Committee (IRC)RET Fusion Positive Thyroid Cancer (TC) Cohort 1Partial Response100.095% Confidence Interval 2.5 to 100.0percentage of participants
Primary Analysis Set: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by Independent Review Committee (IRC)RET Mutant Medullary Thyroid Cancer (MTC) Cohort 2Partial Response50.095% Confidence Interval 29.9 to 70.1percentage of participants
Primary Analysis Set: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by Independent Review Committee (IRC)RET Fusion Positive Non-small Cell Lung Cancer (NSCLC) Cohort 1Overall Response (CR/PR)69.295% Confidence Interval 48.2 to 85.7percentage of participants
Primary Analysis Set: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by Independent Review Committee (IRC)RET Fusion Positive Thyroid Cancer (TC) Cohort 1Overall Response (CR/PR)100.095% Confidence Interval 2.5 to 100.0percentage of participants
Primary Analysis Set: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by Independent Review Committee (IRC)RET Mutant Medullary Thyroid Cancer (MTC) Cohort 2Overall Response (CR/PR)57.795% Confidence Interval 36.9 to 76.6percentage of participants
Enrolled Population: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by IRCNon-small Cell Lung Cancer (All NSCLC)Complete Response6.495% Confidence Interval 1.3 to 17.5percentage of participants
Enrolled Population: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by IRCThyroid Cancer (All TC)Complete Response095% Confidence Interval 0.0 to 97.5percentage of participants
Enrolled Population: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by IRCMedullary Thyroid Cancer (All MTC)Complete Response10.395% Confidence Interval 2.2 to 27.4percentage of participants
Enrolled Population: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by IRCNon-small Cell Lung Cancer (All NSCLC)Partial Response59.695% Confidence Interval 44.3 to 73.6percentage of participants
Enrolled Population: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by IRCThyroid Cancer (All TC)Partial Response100.095% Confidence Interval 2.5 to 100.0percentage of participants
Enrolled Population: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by IRCMedullary Thyroid Cancer (All MTC)Partial Response48.395% Confidence Interval 29.4 to 67.5percentage of participants
Enrolled Population: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by IRCNon-small Cell Lung Cancer (All NSCLC)Overall Response (CR/PR)66.095% Confidence Interval 50.7 to 79.1percentage of participants
Enrolled Population: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by IRCThyroid Cancer (All TC)Overall Response (CR/PR)100.095% Confidence Interval 2.5 to 100.0percentage of participants
Enrolled Population: Overall Response Rate (ORR): Percentage of Participants With Complete Response (CR) or Partial Response (PR) as Assessed by IRCMedullary Thyroid Cancer (All MTC)Overall Response (CR/PR)58.695% Confidence Interval 38.9 to 76.5percentage of participants
Enrolled Population: Duration of Response (DoR) as Assessed by IRCAll NSCLCNA95% Confidence Interval NA to NAmonths
Enrolled Population: Duration of Response (DoR) as Assessed by IRCAll TCNA95% Confidence Interval NA to NAmonths

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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