Trial · NCT04282629
Cerebral Hemodynamic Optimization by Milrinone to Prevent Delayed Cerebral Ischemia
NCT04282629, Phase 2, Active not recruiting, University Hospital, Toulouse
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cerebral Hemodynamic Optimization by Milrinone to Prevent Delayed Cerebral Ischemia. Trials, record NCT04282629. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04282629
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cerebral Hemodynamic Optimization by Milrinone to Prevent Delayed Cerebral Ischemia
- NCT number
- NCT04282629
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 234 participants, estimated
- Lead sponsor
- University Hospital, Toulouse
- Conditions
- Aneurysmal Subarachnoid Hemorrhage
- Interventions
- Milrinone Injection, Placebo
- First posted
- 2020-02-25
- Last updated
- 2026-11-09
Source ClinicalTrials.gov
Registered outcomes22
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | volume of delayed cerebral ischemia lesions | 1 month | volume of DCI lesions measured on CT scan and validated by Magnetic Resonance Imaging (MRI) imaging at 1 month |
| Secondary | Radiological parameters on CT at 1 month | 1 month | percentage of patients with DCI lesions |
| Secondary | Evolution in intensive care: Neurological complications 1 | 1 month | number of episodes of PtiO2 below the ischemic threshold in intensive care: PtiO2 \<20 mmHg (moderate hypoxia) and \<15 mm Hg (severe hypoxia) for at least 15 minutes |
| Secondary | Evolution in intensive care: Neurological complications 2 | 1 month | total duration of episodes of PtiO2 \<20 mm Hg (moderate hypoxia) and \<15 mm Hg (severe hypoxia) |
| Secondary | Evolution in intensive care: Neurological complications 3 | 1 month | number of recourse to an endovascular treatment |
| Secondary | Evolution in intensive care: Neurological complications 4 | 1 month | intracranial hypertension in intensive care: ICP\> 20 mmHg for at least 15 minutes. |
| Secondary | Number and type of non-neurological complications | 1 month | non-neurological complications |
| Secondary | Number of days in intensive care | 1 month | Number of days in intensive care |
| Secondary | Number of days with mechanical ventilation | 1 month | Number of days with mechanical ventilation |
| Secondary | neurological prognosis at 1 month: Rankin score | 1 month | evaluated by the modified Rankin score (good prognosis: mRS 0, 1 and 2 / poor prognosis: mRS 3, 4 and 5) |
1 to 10 of 22Source ClinicalTrials.gov
See all 22 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04282629
GET https://conductscience.org/api/trials/v1/NCT04282629/registered?page=2