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Trial · NCT04305405

Results by group167

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Clearance of BenralizumabAll Participants0.156Standard Deviation 0.0598liter (L) per day
Area Under the Serum Concentration-Time Curve From Time Zero to Day 28 (AUC0-28) of BenralizumabBenralizumab Dose 1, Aged 6-11 Years36918.01Geometric Coefficient of Variation 24.61nanogram*day per milliliter (ng*day/mL)
Area Under the Serum Concentration-Time Curve From Time Zero to Day 28 (AUC0-28) of BenralizumabBenralizumab Dose 2, Aged 6-11 Years75593.37Geometric Coefficient of Variation 39.96nanogram*day per milliliter (ng*day/mL)
Area Under the Serum Concentration-Time Curve From Time Zero to Day 28 (AUC0-28) of BenralizumabBenralizumab Dose 1, Aged 6-14 Years36918.01Geometric Coefficient of Variation 24.61nanogram*day per milliliter (ng*day/mL)
Area Under the Serum Concentration-Time Curve From Time Zero to Day 28 (AUC0-28) of BenralizumabBenralizumab Dose 2, Aged 6-14 Years73670.51Geometric Coefficient of Variation 38.86nanogram*day per milliliter (ng*day/mL)
Maximum Observed Serum Concentration (Cmax) of BenralizumabBenralizumab Dose 1, Aged 6-11 Years1901.18Geometric Coefficient of Variation 28.42ng/mL
Maximum Observed Serum Concentration (Cmax) of BenralizumabBenralizumab Dose 2, Aged 6-11 Years3118.69Geometric Coefficient of Variation 47.35ng/mL
Maximum Observed Serum Concentration (Cmax) of BenralizumabBenralizumab Dose 1, Aged 6-14 Years1901.18Geometric Coefficient of Variation 28.42ng/mL
Maximum Observed Serum Concentration (Cmax) of BenralizumabBenralizumab Dose 2, Aged 6-14 Years3090.85Geometric Coefficient of Variation 43.66ng/mL
Terminal Phase Elimination Half-Life (t1/2) of BenralizumabAll Participants14.4Full Range 6.94 to 23.4day
Time to Achieve Maximum Observed Serum Concentration (Tmax) of BenralizumabBenralizumab Dose 1, Aged 6-11 Years6.91Full Range 0.93 to 14.95day
Time to Achieve Maximum Observed Serum Concentration (Tmax) of BenralizumabBenralizumab Dose 2, Aged 6-11 Years7.26Full Range 1.10 to 14.01day
Time to Achieve Maximum Observed Serum Concentration (Tmax) of BenralizumabBenralizumab Dose 1, Aged 6-14 Years6.91Full Range 0.93 to 14.95day
Time to Achieve Maximum Observed Serum Concentration (Tmax) of BenralizumabBenralizumab Dose 2, Aged 6-14 Years7.94Full Range 1.10 to 14.01day
Trough Concentration of Benralizumab at Week 16 (Ctrough16)Benralizumab Dose 1, Aged 6-11 Years142.42Geometric Coefficient of Variation 256.34ng/mL
Trough Concentration of Benralizumab at Week 16 (Ctrough16)Benralizumab Dose 2, Aged 6-11 Years339.35Geometric Coefficient of Variation 409.24ng/mL
Trough Concentration of Benralizumab at Week 16 (Ctrough16)Benralizumab Dose 1, Aged 6-14 Years142.42Geometric Coefficient of Variation 256.34ng/mL
Trough Concentration of Benralizumab at Week 16 (Ctrough16)Benralizumab Dose 2, Aged 6-14 Years340.46Geometric Coefficient of Variation 363.69ng/mL
Change From Baseline in Peripheral Blood Eosinophil Count up to Week 48Benralizumab Dose 1, Aged 6-11 YearsWeek 4-447.3Standard Deviation 283.76cells/microliters
Change From Baseline in Peripheral Blood Eosinophil Count up to Week 48Benralizumab Dose 2, Aged 6-11 YearsWeek 4-436.9Standard Deviation 408.28cells/microliters

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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