Trial · NCT04335721
Registered outcomes25
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 20 of 25
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in albuminuria in voxelotor-treated SCA patients compared to the observation patients by a one-sided test | 48 weeks | Albuminuria will be analyzed comparing the mean values from the Week 47 and 48 visits to the mean values from the baseline and screening visits |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values in albuminuria | 48 weeks | Proportion of subjects achieving a 25% decline in albuminuria in the voxelotor-treated group compared to the observation group |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values in kidney function measure | 48 weeks | 24 hour urine protein |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values in In kidney function measure | 48 weeks | 24 hour urine eGFR |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values in kidney function measure | 48 weeks | 24 hour urine albumin concentration |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values in kidney function measure | 48 weeks | 24 hour serum creatinine |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values in Kidney function measure | 48 weeks | 24 hour serum cystatin C |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values in Kidney function measure | 48 weeks | 24 hour serum BUN |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values in Kidney function measure | 48 weeks | CKD stage |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values kidney function measure | 48 weeks | 24 hour urine retinol binding protein |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values kidney function measure | 48 weeks | 24 hour urine β2 microglobulin |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values kidney function measure | 48 weeks | Plasma cell-free hemoglobin |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values kidney function measure | 48 weeks | Urine hemoglobin |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values kidney function measure | 48 weeks | Urine dipstick-defined hemoglobinuria) |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values markers of hemolysis | 48 weeks | Lactate dehydrogenase (LDH) |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values markers of hemolysis | 48 weeks | Aspartate aminotransferase (AST) |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values markers of hemolysis | 48 weeks | Indirect bilirubin |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values markers of hemolysis | 48 weeks | Reticulocyte% |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values markers of hemolysis | 48 weeks | Hemoglobin concentration |
| Secondary | Change from the average of the Screening and Baseline values to the Week 47 and Week 48 values kidney injury biomarker | 48 weeks | Urine nephrin |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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GET https://conductscience.org/api/trials/v1/NCT04335721/registered