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Trial · NCT04338321

Results by group882

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants With Remission as Assessed by the Montgomery-Asberg Depression Rating Scale (MADRS) Score at Week 8Esketamine Nasal Spray + Oral Antidepressant (AD)27.1Percentage of participants
Percentage of Participants With Remission as Assessed by the Montgomery-Asberg Depression Rating Scale (MADRS) Score at Week 8Quetiapine Extended Release (XR) + Oral AD17.6Percentage of participants
Percentage of Participants With Both Remission at Week 8 and Relapse-free Until Week 32Esketamine Nasal Spray + Oral Antidepressant (AD)21.7Percentage of Participants
Percentage of Participants With Both Remission at Week 8 and Relapse-free Until Week 32Quetiapine Extended Release (XR) + Oral AD14.1Percentage of Participants
Change From Baseline in Clinician-rated Overall MADRS ScoreEsketamine Nasal Spray + Oral Antidepressant (AD)Week 1-5.3Standard Deviation 5.71Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreQuetiapine Extended Release (XR) + Oral ADWeek 1-3.7Standard Deviation 4.65Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreEsketamine Nasal Spray + Oral Antidepressant (AD)Week 2-9.0Standard Deviation 6.87Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreQuetiapine Extended Release (XR) + Oral ADWeek 2-6.1Standard Deviation 6.52Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreEsketamine Nasal Spray + Oral Antidepressant (AD)Week 4-12.8Standard Deviation 7.50Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreQuetiapine Extended Release (XR) + Oral ADWeek 4-9.8Standard Deviation 7.32Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreEsketamine Nasal Spray + Oral Antidepressant (AD)Week 6-14.9Standard Deviation 8.27Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreQuetiapine Extended Release (XR) + Oral ADWeek 6-12.2Standard Deviation 8.11Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreEsketamine Nasal Spray + Oral Antidepressant (AD)Week 8-16.4Standard Deviation 8.67Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreQuetiapine Extended Release (XR) + Oral ADWeek 8-14.3Standard Deviation 8.26Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreEsketamine Nasal Spray + Oral Antidepressant (AD)Week 10-18.2Standard Deviation 8.32Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreQuetiapine Extended Release (XR) + Oral ADWeek 10-16.2Standard Deviation 7.38Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreEsketamine Nasal Spray + Oral Antidepressant (AD)Week 12-18.4Standard Deviation 8.26Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreQuetiapine Extended Release (XR) + Oral ADWeek 12-16.7Standard Deviation 8.16Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreEsketamine Nasal Spray + Oral Antidepressant (AD)Week 14-19.0Standard Deviation 8.06Unit on scale
Change From Baseline in Clinician-rated Overall MADRS ScoreQuetiapine Extended Release (XR) + Oral ADWeek 14-17.1Standard Deviation 8.06Unit on scale

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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