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Trial · NCT04343963

Pyridostigmine in Severe SARS-CoV-2 Infection

NCT04343963, Phase 2, Phase 3, Unknown, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Pyridostigmine in Severe SARS-CoV-2 Infection. Trials, record NCT04343963. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04343963

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Pyridostigmine in Severe SARS-CoV-2 Infection
NCT number
NCT04343963
Status
Unknown
Phases
Phase 2, Phase 3
Enrollment
436 participants, estimated
Lead sponsor
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Conditions
COVID-19, SARS-CoV-2
Interventions
Pyridostigmine Bromide, Placebo
First posted
2020-04-14
Last updated
2020-07-07

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryCritical condition or death28 daysComposite of death, Need for mechanical ventilation, or an increase of 2 or more points in the SOFA score
PrimaryIL-614 days in-hospital, hospital discharge, or deathKinetics of circulating IL-6

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers11

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
10839541BACKGROUNDPubMed
19645607BACKGROUNDPubMed
25063706BACKGROUNDPubMed
27382171BACKGROUNDPubMed
28416717BACKGROUNDPubMed
31098925BACKGROUNDPubMed
32091533BACKGROUNDPubMed
32105632BACKGROUNDPubMed
32109013BACKGROUNDPubMed
33066761DERIVEDPubMed

1 to 10 of 11

See all 11 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04343963

GET https://conductscience.org/api/trials/v1/NCT04343963/registered