Trial · NCT04345796
Pharmacological Reduction of Right Ventricular Enlargement
NCT04345796, Phase 3, Completed, Asan Medical Center
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Pharmacological Reduction of Right Ventricular Enlargement. Trials, record NCT04345796. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04345796
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Pharmacological Reduction of Right Ventricular Enlargement
- NCT number
- NCT04345796
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 56 participants, actual
- Lead sponsor
- Asan Medical Center
- Conditions
- Tricuspid Regurgitation, Right Ventricular Dilatation
- Interventions
- Carvedilol+Empagliflozin, Carvedilol, Empagliflozin, Placebo
- First posted
- 2020-04-14
- Last updated
- 2025-04-06
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change of RV end-systolic volume index | from baseline to 12 months follow-up | Change of RV end-systolic volume index by cardiac MRI |
| Secondary | Change of RV end-diastolic volume index | from baseline to 12 months follow-up | Change of RV end-diastolic volume index by cardiac MRI |
| Secondary | Change of RV ejection fraction | from baseline to 12 months follow-up | Change of RV ejection fraction by cardiac MRI |
| Secondary | Change of vena contract width of TR | from baseline to 12 months follow-up | Change of vena contract width of TR by echocardiography |
| Secondary | Occurrences of death from cardiovascular causes or hospitalization for heart failure | the entire follow-up period (continuing until 12 months after the last patient was enrolled) | Clinical outcome |
| Secondary | Occurrences of death from any causes | the entire follow-up period (continuing until 12 months after the last patient was enrolled) | Clinical outcome |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 42736580 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04345796
GET https://conductscience.org/api/trials/v1/NCT04345796/registered