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Trial · NCT04349072

Results by group12

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Composite of Decision to Proceed With Septal Reduction Therapy (SRT) and SRT Guideline Eligible at Week 16Mavacamten10Participants
Composite of Decision to Proceed With Septal Reduction Therapy (SRT) and SRT Guideline Eligible at Week 16Placebo to Mavacamten43Participants
Number of Participants With at Least One Class Improvement From Baseline in New York Heart Association (NYHA) Class at Week 16Mavacamten35Participants
Number of Participants With at Least One Class Improvement From Baseline in New York Heart Association (NYHA) Class at Week 16Placebo to Mavacamten12Participants
Change From Baseline to Week 16 in Kansas City Cardiomyopathy Questionnaire 23-item Version, Clinical Summary Score (KCCQ-23, CSS)Mavacamten10.4Standard Deviation 16.06Score on a scale
Change From Baseline to Week 16 in Kansas City Cardiomyopathy Questionnaire 23-item Version, Clinical Summary Score (KCCQ-23, CSS)Placebo to Mavacamten1.8Standard Deviation 12.01Score on a scale
Change From Baseline to Week 16 in N-Terminal Pro-b-Type Natriuretic Peptide (NT-proBNP)Mavacamten0.35Geometric Coefficient of Variation NAng/L
Change From Baseline to Week 16 in N-Terminal Pro-b-Type Natriuretic Peptide (NT-proBNP)Placebo to Mavacamten1.13Geometric Coefficient of Variation NAng/L
Change From Baseline to Week 16 in Cardiac TroponinMavacamten0.50Geometric Coefficient of Variation NAng/L
Change From Baseline to Week 16 in Cardiac TroponinPlacebo to Mavacamten1.03Geometric Coefficient of Variation NAng/L
Change From Baseline to Week 16 in Post-Exercise Left Ventricular Outflow Tract (LVOT) GradientMavacamten-39.1Standard Deviation 36.51mmHg
Change From Baseline to Week 16 in Post-Exercise Left Ventricular Outflow Tract (LVOT) GradientPlacebo to Mavacamten-1.8Standard Deviation 28.82mmHg

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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