Trial · NCT04358991
Pharmacokinetics of Ceftazidime-avibactam Among Critically-ill Patients Receiving CVVHDF
NCT04358991, Completed, University of Pittsburgh; results first posted 2020-05-15
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Pharmacokinetics of Ceftazidime-avibactam Among Critically-ill Patients Receiving CVVHDF. Trials, record NCT04358991. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04358991
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Pharmacokinetics of Ceftazidime-avibactam Among Critically-ill Patients Receiving CVVHDF
- NCT number
- NCT04358991
- Status
- Completed
- Enrollment
- 20 participants, actual
- Lead sponsor
- University of Pittsburgh
- Conditions
- Bacterial Infections
- Interventions
- Ceftazidime-avibactam
- First posted
- 2020-04-24
- Last updated
- 2020-09-29
- Results first posted
- 2020-05-15
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Serum Levels of Ceftazidime and Avibactam Among Critically-ill Patients | 8 hours | PK samples obtained around standard of care dosing regimens immediately before and at 1, 2, 4, 6, and 8 hours after administration |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Serum Levels of Ceftazidime and Avibactam Among Critically-ill Patients | 8 hours | mcg/mL | MEDIAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Serum Levels of Ceftazidime and Avibactam Among Critically-ill Patients | Subjects Included | Ceftazidime Cmax | 80.6 | Inter-Quartile Range 61.2 to 104.1 | mcg/mL |
| Serum Levels of Ceftazidime and Avibactam Among Critically-ill Patients | Subjects Included | Avibactam Cmax | 15.9 | Inter-Quartile Range 11.8 to 23.0 | mcg/mL |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Subjects Included | 20 | |
| Overall Study | COMPLETED | Subjects Included | 20 | |
| Overall Study | NOT COMPLETED | Subjects Included | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Subjects Included | 3 | 20 |
| Total, other adverse events | Subjects Included | 0 | 20 |
| Total, serious adverse events | Subjects Included | 0 | 20 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04358991
GET https://conductscience.org/api/trials/v1/NCT04358991/registered