Trial · NCT04370262
Multi-site Adaptive Trials for COVID-19
NCT04370262, Phase 3, Completed, Northwell Health
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Multi-site Adaptive Trials for COVID-19. Trials, record NCT04370262. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04370262
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Multi-site Adaptive Trials for COVID-19
- NCT number
- NCT04370262
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 233 participants, actual
- Lead sponsor
- Northwell Health
- Conditions
- COVID-19
- Interventions
- SOC + Intravenous Famotidine, SOC + Placebo
- First posted
- 2020-04-30
- Last updated
- 2020-12-11
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Mortality | 30 days post hospitalization | Mortality status |
| Secondary | Virologic response to study treatment detected in blood | Day 30 relative to admission Day 0 | Percent change in PCR copy number from first measurement |
| Secondary | Virologic clearance in nasal swab and/or lower respiratory secretions | Day 6 and Day 30 | Presence or absence of SARS-CoV-2 Viral RNA in Nasopharyngeal swab or lower respiratory secretions |
| Secondary | Clinical Severity | Measured on study Days 3, 5, 8, 11, 15 and 30. | Measured by 7-point ordinal scale: from (1) death, to (7) not hospitalized, no limit on daily activities |
| Secondary | Clinical Severity | Measured on study Days 3, 5, 8, 11, 15 and 30. | Measured by National Early Warning Score (NEWS): vital sign based score from 0-20, higher score indicates higher degree of illness |
| Secondary | Clinical Severity | Measured on study Days 3, 5, 8, 11, 15 and 30. | Measured by duration of use of supplemental oxygen (if applicable) |
| Secondary | Clinical Severity | Measured on study Days 3, 5, 8, 11, 15 and 30. | Measured by duration of use of mechanical ventilation (if applicable) |
| Secondary | Clinical Severity | Measured on study Days 3, 5, 8, 11, 15 and 30. | Measured by duration of hospitalization |
| Other | Incidence of New Onset Lymphopenia | Through study completion, average of 30 days | Incidence of new onset lymphopenia during hospitalization measured by blood draw |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers11
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04370262
GET https://conductscience.org/api/trials/v1/NCT04370262/registered