Trial · NCT04373941
Part II: Granulocyte-Colony Stimulating Factor Adjunct Therapy for Biliary Atresia
NCT04373941, Phase 2, Unknown, Holterman, Ai-Xuan, M.D.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Part II: Granulocyte-Colony Stimulating Factor Adjunct Therapy for Biliary Atresia. Trials, record NCT04373941. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04373941
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Part II: Granulocyte-Colony Stimulating Factor Adjunct Therapy for Biliary Atresia
- NCT number
- NCT04373941
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 400 participants, estimated
- Lead sponsor
- Holterman, Ai-Xuan, M.D.
- Conditions
- Biliary Atresia
- Interventions
- Filgrastim
- First posted
- 2020-05-05
- Last updated
- 2023-09-08
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | GCSF Response on Bile flow (KBA) | 3 months | For KBA subjects: Bile flow as measured by the percentage of subjects with total bilirubin\< 2 mg/dL at 3 months post-Kasai. |
| Primary | GCSF Response on transplant-free survival (NoK) | 24 months | For NoK subjects: Changes at 6, 12, 18 and 24 months-transplant free survival |
| Secondary | GCSF response on liver function and outcome (KBA) | 24 months | KBA subjects: Pediatric end-stage liver disease (PELD) score at 6, 12, 18, and 24 months after GCSF treatment. |
| Secondary | GCSF response on liver function and outcome (KBA) | 24 months | KBA subjects: Percentage of patients with transplant-free survival at 6, 12, 18 and 24 months |
| Secondary | GCSF response on liver function and outcome (KBA) | 24 months | KBA subjects: Percentage of patients with cholangitis-free transplant-free survival at 6, 12, 18 and 24 months |
| Secondary | GCSF response on liver function (NoK) | 24 months | NoK subjects: Changes in Pediatric end-stage liver disease (PELD) score at 6, 12, 18, and 24 months after GCSF treatment. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers9
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04373941
GET https://conductscience.org/api/trials/v1/NCT04373941/registered