ConductScience.org, home

Trial · NCT04395950

Effects of ACC Inhibitor on Lipid and Lipoprotein Metabolism

NCT04395950, Phase 1, Withdrawn, Columbia University

3 sourcestrials-2026-11-12-0.5.0

Download JSON
Cite this record

ConductScience Library. Effects of ACC Inhibitor on Lipid and Lipoprotein Metabolism. Trials, record NCT04395950. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04395950

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Effects of ACC Inhibitor on Lipid and Lipoprotein Metabolism
NCT number
NCT04395950
Status
Withdrawn
Phases
Phase 1
Enrollment
0 participants, actual
Lead sponsor
Columbia University
Conditions
NASH (Nonalcoholic Steatohepatitis), NAFLD (Nonalcoholic Fatty Liver Disease)
Interventions
PF-05221304, Placebo
First posted
2020-05-20
Last updated
2021-08-25

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryRate of Secretion (also called production-PR) of VLDL TG (mg/kg/day)Up to 20 weeksThis is also called the production rate of very low density lipoprotein (VLDL) triglycerides (TG).
PrimaryFractional Clearance Rate (FCR) of VLDL TG (pool/day)Up to 20 weeksThis is obtained from the modeling of enrichment data obtained by mass spectrometry.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers9

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
10362629BACKGROUNDPubMed
14631324BACKGROUNDPubMed
15864352BACKGROUNDPubMed
18515257BACKGROUNDPubMed
18640385BACKGROUNDPubMed
21616678BACKGROUNDPubMed
26819195BACKGROUNDPubMed
28768177BACKGROUNDPubMed
29790582BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04395950

GET https://conductscience.org/api/trials/v1/NCT04395950/registered