Trial · NCT04399122
Post-operative Pain Control After Photorefractive Keratectomy Comparing Acetaminophen/Codeine vs Acetaminophen/Oxycodone
NCT04399122, Phase 4, Completed, 59th Medical Wing; results first posted 2021-10-05
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Post-operative Pain Control After Photorefractive Keratectomy Comparing Acetaminophen/Codeine vs Acetaminophen/Oxycodone. Trials, record NCT04399122. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04399122
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Post-operative Pain Control After Photorefractive Keratectomy Comparing Acetaminophen/Codeine vs Acetaminophen/Oxycodone
- NCT number
- NCT04399122
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 200 participants, actual
- Lead sponsor
- 59th Medical Wing
- Conditions
- Post-operative Pain Control
- Interventions
- acetaminophen/codeine vs acetaminophen/oxycodone
- First posted
- 2020-05-22
- Last updated
- 2021-10-05
- Results first posted
- 2021-10-05
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Post-operative Average Pain Score | 2 days post surgery | The PRK Post-Operative Pain Survey consisted of a scale of 0 - 10 with a score of 0 equal to no pain, a score of 1 - 3 equal to mild pain, a score of 4 - 6 equal to moderate pain and a score of 7 - 10 equal to severe pain |
| Secondary | Post-operative Uncorrected Visual Acuity Right and Left Eye | Post-operative month 6. | Right and left eye uncorrected visual acuity at post-operative month 6. |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Post-operative Average Pain Score | 2 days post surgery | units on a scale | MEAN | |
| SECONDARY | Post-operative Uncorrected Visual Acuity Right and Left Eye | Post-operative month 6. | logMAR | MEAN |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Post-operative Average Pain Score | Acetaminophen With Codeine | 2.82 | Standard Deviation 2.03 | units on a scale | |
| Post-operative Average Pain Score | Acetaminophen With Oxycodone | 3.58 | Standard Deviation 2.29 | units on a scale | |
| Post-operative Uncorrected Visual Acuity Right and Left Eye | Acetaminophen With Codeine | Right Eye logMAR | -0.07 | Standard Deviation 0.01 | logMAR |
| Post-operative Uncorrected Visual Acuity Right and Left Eye | Acetaminophen With Oxycodone | Right Eye logMAR | -0.05 | Standard Deviation 0.01 | logMAR |
| Post-operative Uncorrected Visual Acuity Right and Left Eye | Acetaminophen With Codeine | Left Eye logMAR | -0.06 | Standard Deviation 0.01 | logMAR |
| Post-operative Uncorrected Visual Acuity Right and Left Eye | Acetaminophen With Oxycodone | Left Eye logMAR | -0.06 | Standard Deviation 0.01 | logMAR |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Acetaminophen With Codeine | 100 | |
| Overall Study | STARTED | Acetaminophen With Oxycodone | 100 | |
| Overall Study | COMPLETED | Acetaminophen With Codeine | 97 | |
| Overall Study | COMPLETED | Acetaminophen With Oxycodone | 100 | |
| Overall Study | NOT COMPLETED | Acetaminophen With Codeine | 3 | |
| Overall Study | NOT COMPLETED | Acetaminophen With Oxycodone | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Acetaminophen With Codeine | 0 | 97 |
| Total, all-cause mortality | Acetaminophen With Oxycodone | 0 | 100 |
| Total, other adverse events | Acetaminophen With Codeine | 0 | 97 |
| Total, other adverse events | Acetaminophen With Oxycodone | 0 | 100 |
| Total, serious adverse events | Acetaminophen With Codeine | 0 | 97 |
| Total, serious adverse events | Acetaminophen With Oxycodone | 0 | 100 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Acetaminophen With Codeine vs Acetaminophen With Oxycodone: deaths from any cause | Trial comparisons |
| Acetaminophen With Codeine vs Acetaminophen With Oxycodone: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04399122
GET https://conductscience.org/api/trials/v1/NCT04399122/registered