Trial · NCT04408313
Extended Release Naltrexone Versus Extended Release Buprenorphine With Individuals Leaving Jail
NCT04408313, Phase 2, Phase 3, Active not recruiting, Friends Research Institute, Inc.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Extended Release Naltrexone Versus Extended Release Buprenorphine With Individuals Leaving Jail. Trials, record NCT04408313. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04408313
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Extended Release Naltrexone Versus Extended Release Buprenorphine With Individuals Leaving Jail
- NCT number
- NCT04408313
- Status
- Active not recruiting
- Phases
- Phase 2, Phase 3
- Enrollment
- 240 participants, estimated
- Lead sponsor
- Friends Research Institute, Inc.
- Conditions
- Opioid-use Disorder
- Interventions
- XR-B, XR-NTX
- First posted
- 2020-05-29
- Last updated
- 2026-05-05
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | pharmacotherapy adherence | 6-months post-release | number of monthly injections received (0-6) |
| Secondary | illicit opioid urine screening test results | 1-7,12-months | number of illicit opioid positive urine drug screen results |
| Secondary | self-reported illicit opioid use | Baseline, 1-7,12-months | self reported days of illicit opioid use |
| Secondary | overdose events | Baseline, 1-7,12-months | number of fatal and non-fatal overdoses |
| Secondary | Patient-Reported Outcomes Measurement Information System | Baseline, 1-7,12-months | physical, mental, and social health * scored 0: Death * scored \< 1: A state worse than perfect health |
| Secondary | Risk Assessment Battery (RAB) | Baseline, 1-7,12-months | HIV risk behaviors; total score/40 (range=0-1) |
| Secondary | Criminal activity | Baseline, 1-7,12-months | number of days committed crime (20 crimes) |
| Secondary | Re-arrest | 12-months | time to rearrest (days to arrest) |
| Secondary | Re-incarceration | 12-months | time to re-incarceration (days to re-incarceration) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 40342086 | DERIVED |
Source PubMed
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| UG1DA050077 | A comparative effectiveness trial of extended release naltrexone versus extended-release buprenorphine with individuals leaving jail | GORDON, MICHAEL SCOTT; BLUE, THOMAS | FRIENDS RESEARCH INSTITUTE, INC. | NATIONAL INSTITUTE ON DRUG ABUSE | 2019 to 2023 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04408313
GET https://conductscience.org/api/trials/v1/NCT04408313/registered