Trial · NCT04409522
Evaluation of Therapeutic Effects of Melatonin by Inhibition of NLRP3 Inflammasome in COVID19 Patients
NCT04409522, Not applicable, Unknown, Mohammad Sadegh Bagheri Baghdasht
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Evaluation of Therapeutic Effects of Melatonin by Inhibition of NLRP3 Inflammasome in COVID19 Patients. Trials, record NCT04409522. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04409522
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Evaluation of Therapeutic Effects of Melatonin by Inhibition of NLRP3 Inflammasome in COVID19 Patients
- NCT number
- NCT04409522
- Status
- Unknown
- Phases
- Not applicable
- Enrollment
- 55 participants, estimated
- Lead sponsor
- Mohammad Sadegh Bagheri Baghdasht
- Conditions
- COVID-19
- Interventions
- Melatonin, The usual treatment
- First posted
- 2020-06-01
- Last updated
- 2020-06-01
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Melatonin | up to 10 days | Immune system modulator. The amount of it is determined by laboratory methods |
| Secondary | Inflammatory cytokines | up to 10 days | is a type of signaling molecule (a cytokine) that is secreted from immune cells like helper T cells (Th) and macrophages, and certain other cell types that promote inflammation which is measured by serological or analyzer method |
| Secondary | C-reactive protein (CRP) | up to 10 days | C-reactive protein (CRP) is a protein made by the liver that measured by serological or analyzer method |
| Secondary | Cough | up to 10 days | A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions that measured by Physical examination. |
| Secondary | Oxygen saturation of the blood | up to 10 days | Oxygen saturation of the blood will measure by pulse oximeter |
| Secondary | ESR | up to 10 days | Red blood cell sedimentation rate will measure by Autoanalyzer |
| Secondary | Radiological Treatment Response | up to 10 days | Radiological Treatment Response (CT scan), more than 50% reduction in the affected area |
| Secondary | Inflammatory route | up to 10 days | Cellular pathway active in inflammation |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04409522
GET https://conductscience.org/api/trials/v1/NCT04409522/registered