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Trial · NCT04411472

Outcomes16

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARY28-day All-cause Mortality: Main Trial Population28 daysMain Trial modified intent-to-treat PopulationParticipantsCOUNT_OF_PARTICIPANTS
PRIMARY28-day All-cause Mortality: Moderate Chronic Kidney Disease Population28 daysModerate Chronic Kidney Disease modified intent-to-treat PopulationParticipantsCOUNT_OF_PARTICIPANTS
PRIMARY28-day All-cause Mortality: COVID-19 Population28 daysCOVID-19 modified intent-to-treat PopulationParticipantsCOUNT_OF_PARTICIPANTS
SECONDARYMajor Adverse Kidney Events 90: Main Trial Population90 DaysMain Trial modified intent-to-treat PopulationParticipantsCOUNT_OF_PARTICIPANTS
SECONDARYMajor Adverse Kidney Events 90: Moderate Chronic Kidney Disease Population90 DaysModerate Chronic Kidney Disease modified intent-to-treat PopulationParticipantsCOUNT_OF_PARTICIPANTS
SECONDARYMajor Adverse Kidney Events 90: COVID-19 Population90 DaysCOVID-19 modified intent-to-treat PopulationParticipantsCOUNT_OF_PARTICIPANTS
SECONDARYMajor Adverse Kidney Events Through Day 90: Combined Population90 Days
Combined population: From the 650 patients in the mITT population (321 Placebo and 329 recAP), 649 were analysed in the combined population (1 participant randomized and treated with placebo has been excluded as no efficacy data were available). In the combined population participants were analyzed as treated, resulting in 319 Placebo and 330 recAP participants (2 participants randomized to Placebo were treated with recAP, 1 participant randomized to recAP was treated with placebo).
ParticipantsCOUNT_OF_PARTICIPANTS
SECONDARYDays Alive and Free of Organ Support Through Day 28: Main Trial Population28 daysMain Trial modified intent-to-treat PopulationdaysMEAN
SECONDARYDays Alive and Free of Organ Support Through Day 28: Moderate Chronic Kidney Disease Population28 daysModerate Chronic Kidney Disease modified intent-to-treat PopulationdaysMEAN
SECONDARYDays Alive and Free of Organ Support Through Day 28: COVID-19 Population28 daysCOVID-19 modified intent-to-treat PopulationdaysMEAN
SECONDARYDays Alive and Out of the ICU Through Day 28: Main Trial Population28 daysMain Trial modified intent-to-treat PopulationDaysMEAN
SECONDARYDays Alive and Out of the ICU Through Day 28: Moderate Chronic Kidney Disease Population28 daysModerate Chronic Kidney Disease modified intent-to-treat PopulationDaysMEAN
SECONDARYDays Alive and Out of the ICU Through Day 28: COVID-19 Population28 daysCOVID-19 modified intent-to-treat PopulationDaysMEAN
SECONDARY90-day All Cause Mortality: Main Trial Population90 daysMain Trial modified intent-to-treat PopulationParticipantsCOUNT_OF_PARTICIPANTS
SECONDARY90-day All Cause Mortality: Moderate Chronic Kidney Disease Population90 daysModerate Chronic Kidney Disease modified intent-to-treat PopulationParticipantsCOUNT_OF_PARTICIPANTS
SECONDARY90-day All Cause Mortality: COVID-19 Population90 daysCOVID-19 modified intent-to-treat PopulationParticipantsCOUNT_OF_PARTICIPANTS

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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