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A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors
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Trial · NCT04434092

Participant flow18

How many started, completed or left each group, period by period.

1 to 18 of 18

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PeriodMilestoneGroupParticipantsUnits counted
Primary Treatment Period:Baseline-Week24STARTEDArm A: Crovalimab135
Primary Treatment Period:Baseline-Week24STARTEDArm B: Eculizumab69
Primary Treatment Period:Baseline-Week24STARTEDArm C: Crovalimab6
Primary Treatment Period:Baseline-Week24COMPLETEDArm A: Crovalimab129
Primary Treatment Period:Baseline-Week24COMPLETEDArm B: Eculizumab68
Primary Treatment Period:Baseline-Week24COMPLETEDArm C: Crovalimab6
Primary Treatment Period:Baseline-Week24NOT COMPLETEDArm A: Crovalimab6
Primary Treatment Period:Baseline-Week24NOT COMPLETEDArm B: Eculizumab1
Primary Treatment Period:Baseline-Week24NOT COMPLETEDArm C: Crovalimab0
Extension Treatment Period:Week 25-5 YrsSTARTEDArm A: Crovalimab129
Extension Treatment Period:Week 25-5 YrsSTARTEDArm B: Eculizumab68
Extension Treatment Period:Week 25-5 YrsSTARTEDArm C: Crovalimab6
Extension Treatment Period:Week 25-5 YrsCOMPLETEDArm A: Crovalimab0
Extension Treatment Period:Week 25-5 YrsCOMPLETEDArm B: Eculizumab0
Extension Treatment Period:Week 25-5 YrsCOMPLETEDArm C: Crovalimab0
Extension Treatment Period:Week 25-5 YrsNOT COMPLETEDArm A: Crovalimab129
Extension Treatment Period:Week 25-5 YrsNOT COMPLETEDArm B: Eculizumab68
Extension Treatment Period:Week 25-5 YrsNOT COMPLETEDArm C: Crovalimab6

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/trials/v1/NCT04434092/flow

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