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Trial · NCT04435366

Results by group43

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
The Mean Rate of Growth (Slope) Estimated Based on GA Area Measured by Autofluorescence (FAF) at 3 Time Points: Baseline, Month 6, and Month 12Avacincaptad Pegol0.336Standard Error 0.032millimeters (mm)/year
The Mean Rate of Growth (Slope) Estimated Based on GA Area Measured by Autofluorescence (FAF) at 3 Time Points: Baseline, Month 6, and Month 12Sham0.392Standard Error 0.033millimeters (mm)/year
The Mean Rate of Growth (Slope) Estimated Based on GA Area Measured by FAF at 5 Timepoints: Baseline, Month 6, Month 12, Month 18, and Month 24Avacincaptad Pegol2.23Standard Error 0.124mm^2/year
The Mean Rate of Growth (Slope) Estimated Based on GA Area Measured by FAF at 5 Timepoints: Baseline, Month 6, Month 12, Month 18, and Month 24Avacincaptad Pegol and Sham2.10Standard Error 0.126mm^2/year
The Mean Rate of Growth (Slope) Estimated Based on GA Area Measured by FAF at 5 Timepoints: Baseline, Month 6, Month 12, Month 18, and Month 24Sham2.59Standard Error 0.085mm^2/year
Change From Baseline in Best Corrected Visual Acuity (BCVA) Using Early Treatment Diabetic Retinopathy Study (ETDRS) Letters at 24 MonthsAvacincaptad Pegol-7.31Standard Error 1.07score on a scale
Change From Baseline in Best Corrected Visual Acuity (BCVA) Using Early Treatment Diabetic Retinopathy Study (ETDRS) Letters at 24 MonthsSham-6.48Standard Error 1.05score on a scale
Change From Baseline in Low Luminance (LL) BCVA Using ETDRS Letters at 24 MonthsAvacincaptad Pegol-10.58Standard Error 1.20score on a scale
Change From Baseline in Low Luminance (LL) BCVA Using ETDRS Letters at 24 MonthsSham-9.1Standard Error 1.18score on a scale
Change From Baseline in Visual Function Questionnaire (VFQ-25) Composite Scores at 6, 12 and 18 MonthsAvacincaptad PegolChange at 6 months-1.2Standard Deviation 10.56score on a scale
Change From Baseline in Visual Function Questionnaire (VFQ-25) Composite Scores at 6, 12 and 18 MonthsShamChange at 6 months-1.6Standard Deviation 9.98score on a scale
Change From Baseline in Visual Function Questionnaire (VFQ-25) Composite Scores at 6, 12 and 18 MonthsAvacincaptad PegolChange at 12 months-3.4Standard Deviation 11.05score on a scale
Change From Baseline in Visual Function Questionnaire (VFQ-25) Composite Scores at 6, 12 and 18 MonthsShamChange at 12 months-3.6Standard Deviation 11.01score on a scale
Change From Baseline in Visual Function Questionnaire (VFQ-25) Composite Scores at 6, 12 and 18 MonthsAvacincaptad PegolChange at 18 months-5.4Standard Deviation 12.80score on a scale
Change From Baseline in Visual Function Questionnaire (VFQ-25) Composite Scores at 6, 12 and 18 MonthsShamChange at 18 months-4.7Standard Deviation 11.53score on a scale
Change From Baseline in Visual Function Questionnaire (VFQ-25) Composite Scores at 24 MonthsAvacincaptad Pegol-7.735Standard Error 0.950score on a scale
Change From Baseline in Visual Function Questionnaire (VFQ-25) Composite Scores at 24 MonthsSham-7.023Standard Error 0.931score on a scale
Number of Participants With Categorical One-level Loss in VFQ-25 SubscaleAvacincaptad PegolColor Vision45participants
Number of Participants With Categorical One-level Loss in VFQ-25 SubscaleShamColor Vision35participants
Number of Participants With Categorical One-level Loss in VFQ-25 SubscaleAvacincaptad PegolDistance Vision56participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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