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Trial · NCT04447989

Results by group85

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Safety Based Upon Number of Participants With HypotensionCohort 1, Sildenafil1Participants
Safety Based Upon Number of Participants With HypotensionCohort 2, Sildenafil0Participants
Safety Based Upon Number of Participants With HypotensionCohort 3, Sildenafil0Participants
Safety Based Upon Number of Participants With HypotensionPlacebo0Participants
Central Volume of Distribution (Vc) Population Pharmacokinetics (popPK)Pharmacokinetics (PK) Cohort3.8695% Confidence Interval 1.28 to 11.07L
Peripheral Volume of Distribution (Vp) Population Pharmacokinetics (popPK)Pharmacokinetics (PK) Cohort4.4995% Confidence Interval 2.87 to 6.66L
Clearance Population Pharmacokinetics (popPK)Pharmacokinetics (PK) Cohort2.6995% Confidence Interval 1.00 to 7.94L/h
Half-life Population Pharmacokinetics (popPK)Pharmacokinetics (PK) Cohort8.79Inter-Quartile Range 8.00 to 9.42hours
Peak Plasma Concentration Population Pharmacokinetics (popPK)Pharmacokinetics (PK) Cohort130.5Inter-Quartile Range 70.9 to 256.0ng/mL
Number of Participants at Each Global RankCohort 1, SildenafilMortality0Participants
Number of Participants at Each Global RankCohort 2, SildenafilMortality2Participants
Number of Participants at Each Global RankCohort 3, SildenafilMortality1Participants
Number of Participants at Each Global RankPlaceboMortality0Participants
Number of Participants at Each Global RankCohort 1, SildenafilExtracorporeal life support0Participants
Number of Participants at Each Global RankCohort 2, SildenafilExtracorporeal life support0Participants
Number of Participants at Each Global RankCohort 3, SildenafilExtracorporeal life support0Participants
Number of Participants at Each Global RankPlaceboExtracorporeal life support0Participants
Number of Participants at Each Global RankCohort 1, SildenafilTracheostomy8Participants
Number of Participants at Each Global RankCohort 2, SildenafilTracheostomy3Participants
Number of Participants at Each Global RankCohort 3, SildenafilTracheostomy4Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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