Trial · NCT04465123
Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study
NCT04465123, Phase 3, Unknown, Chiang Mai University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study. Trials, record NCT04465123. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04465123
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study
- NCT number
- NCT04465123
- Status
- Unknown
- Phases
- Phase 3
- Enrollment
- 100 participants, estimated
- Lead sponsor
- Chiang Mai University
- Conditions
- Acute Heart Failure, Acute Kidney Injury
- Interventions
- Spironolactone or hydrochlorothiazide, Placebo
- First posted
- 2020-07-09
- Last updated
- 2020-08-18
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Urine volume | 72 hours | Total urine volume after randomisation |
| Secondary | Urine volume | 24 and 48 hours | Total urine volume after randomization |
| Secondary | Body weight | 72 hours after randomisation | Changes of patient's body weight |
| Secondary | Length of hospital admission | During hospital admission period | Number of days that patients need to stay in the hospital |
| Secondary | Furosemide dose | 72 hours after randomisation | Total dosage of intravenous furosemide |
| Secondary | Levels of B-type atrial natriuretic peptide (BNP) | 72 hours and 7 days after randomisation | levels of pro-BNP |
| Secondary | Number of participants with adverse events | During hospital admission | All adverse events during hospital admission |
| Secondary | Dyspnea score assessed by visual analogue scale | At randomization, and 6, 12, 24, 48 and 72 hours after randomization | The scale is between 0 and 100. The higher scale represents lower level of dyspnea |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04465123
GET https://conductscience.org/api/trials/v1/NCT04465123/registered