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Trial · NCT04472637

Atorvastatin Effects On Arterial Stiffness In Hemodialysis

NCT04472637, Phase 2, Completed, Alexandria University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Atorvastatin Effects On Arterial Stiffness In Hemodialysis. Trials, record NCT04472637. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04472637

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Atorvastatin Effects On Arterial Stiffness In Hemodialysis
NCT number
NCT04472637
Status
Completed
Phases
Phase 2
Enrollment
50 participants, actual
Lead sponsor
Alexandria University
Conditions
Arterial Stiffness
Interventions
Atorvastatin, Placebo
First posted
2020-07-15
Last updated
2022-04-15

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primarychange in Aortic pulse wave velocity (PWV)baseline, 24 weeks
the procedure was done at least 30 minutes after the dialysis session. Measurements were made after 10 minutes of rest in a supine position with a suitable cuff placed in the upper arm (the non-arteriovenous fistula arm in the hemodialysis group) and a connecting tube linking the cuff to a recorder device.Three consecutive measurements were taken automatically with 30 seconds of duration.
Primarychange in Augmentation index (AIx)baseline, 24 weeksIt is a surrogate index of arterial stiffness which measures pulse wave reflections that significantly influence the central pressure profile. It is directly related to peripheral arterial stiffness.
Secondarychange in Central systolic blood pressure (CSP)24 weeksCentral aortic systolic blood pressure is a parameter that strongly reflects vascular changes of central elastic arteries compared to peripheral brachial blood pressure
Secondarychange in Peripheral blood pressure (PBP)baseline, 24 weekschange in peripheral systolic and diastolic blood pressure
Secondarychange in central pulse pressure (PP)baseline, 24 weekswill be clalculated from the central waveform

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers15

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
10318666BACKGROUNDPubMed
11423581BACKGROUNDPubMed
15102961BACKGROUNDPubMed
17138941BACKGROUNDPubMed
17430220BACKGROUNDPubMed
19451808BACKGROUNDPubMed
20032570BACKGROUNDPubMed
20237499BACKGROUNDPubMed
21660313BACKGROUNDPubMed
22534962BACKGROUNDPubMed

1 to 10 of 15

See all 15 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04472637

GET https://conductscience.org/api/trials/v1/NCT04472637/registered