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Trial · NCT04514458

Registered outcomes18

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPercentage of Patients With Heart Failure With Reduced Ejection Fraction (HFrEF) With an Increase in Prescribed HFrEF TherapyAssessed from the date of randomization to 30 days post-randomizationAssessed as an increase in the number of prescribed targeted evidence-based therapies for HFrEF, including beta-blockers, ACEi, ARBs, ARNIs, MRAs, and SGLT2is.
SecondaryPercentage of Patients on Beta BlockersAssessed from the date of randomization to 30 days post-randomizationAssessed as the number of patients with prescribed beta blockers
SecondaryPercentage of Patients on ACE InhibitorsAssessed from the date of randomization to 30 days post-randomizationAssessed as the number of patients with a prescribed ACEi
SecondaryPercentage of Patients on ARBsAssessed from the date of randomization to 30 days post-randomizationAssessed as the number of patients with a prescribed ARB
SecondaryPercentage of Patients on ARNIsAssessed from the date of randomization to 30 days post-randomizationAssessed as the number of patients with a prescribed ARNI
SecondaryPercentage of Patients on MRAsAssessed from the date of randomization to 30 days post-randomizationAssessed as the number of patients with a prescribed MRA
SecondaryPercentage of Patients on SGLT2 InhibitorsAssessed from the date of randomization to 30 days post-randomizationAssessed as the number of patients with a prescribed SGLT2i
SecondaryRate of One-year All-cause MortalityAssessed from the date of randomization to the date of death from any cause, up to 365 days post-randomizationAssessed as the number of patients who expired from randomization up to one year from any cause.
SecondaryRate of 30-day Hospital AdmissionAssessed from the date of randomization to the date of hospital admission, up to 30 days post-randomizationNumber of participants with a hospitalization within 30 days of randomization
SecondaryRate of 30-day All-cause Emergency Department VisitsAssessed from the date of randomization to the date of ED/ER admission, up to 30 days post-randomizationNumber of participants with an emergency department visit within 30 days of randomization.
SecondaryTotal Six-month Healthcare CostsAssessed from the date of randomization to 6 months post-randomizationAssessed as total direct and indirect cost of patient care from randomization to 6 months post randomization.
SecondaryPercentage of Filled PrescriptionsAssessed 6 months post-randomizationProportion of prescriptions filled as assessed by SureScripts
SecondaryMedication Dose of Any Prescribed Beta BlockerAssessed at 6 months post-randomization
SecondaryMedication Dose of Any Prescribed ACEiAssessed at 6 months post-randomization
SecondaryMedication Dose of Any Prescribed ARBAssessed at 6 months post-randomization
SecondaryMedication Dose of Any Prescribed ARNIAssessed at 6 months post-randomization
SecondaryMedication Dose of Any Prescribed MRAAssessed at 6 months post-randomization
SecondaryMedication Dose of Any Prescribed SGLT2 InhibitorAssessed at 6 months post-randomization

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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