Trial · NCT04521881
Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults
NCT04521881, Phase 3, Recruiting, London School of Hygiene and Tropical Medicine
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults. Trials, record NCT04521881. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04521881
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults
- NCT number
- NCT04521881
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 5,000 participants, estimated
- Lead sponsor
- London School of Hygiene and Tropical Medicine
- Conditions
- Traumatic Brain Injury
- Interventions
- Tranexamic Acid 500 MG
- First posted
- 2020-08-21
- Last updated
- 2026-03-12
- Other registries' IDs
- eudract:2020-003391-40
Source ClinicalTrials.gov
Registered outcomes16
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Emergency department discharge | within 24 hours | discharge |
| Secondary | Intracranial bleeding on CT scan | within 48 hours | any bleeding on the last scan conducted within 48 hours of randomisation |
| Secondary | Head injury related death | within 48 hours | In-hospital head injury-related death within 48 hours of injury |
| Secondary | All cause mortality | within 28 days | Cause of death will be described |
| Secondary | Disability | within 28 days | The Barthel scale will be used to assess functional disability |
| Secondary | Global assessment of ability to self-care | within 28 days | Scale of 1 to 5 |
| Secondary | Neurosurgery | within 28 days | receipt of neurosurgery and type |
| Secondary | Days in ICU | within 28 days | Number of days |
| Secondary | Re-admission to hospital | within 28 days | readmission after discharge |
| Secondary | Vascular occlusive events | within 28 days | pulmonary embolism, myocardial infarction, deep vein thrombosis and stroke |
1 to 10 of 16Source ClinicalTrials.gov
See all 16 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04521881
GET https://conductscience.org/api/trials/v1/NCT04521881/registered