Trial · NCT04528056
Pilot Study of the Safety and Efficacy of Sulfasalazine in Pulmonary Arterial Hypertension
NCT04528056, Phase 1, Phase 2, Unknown, RenJi Hospital
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Pilot Study of the Safety and Efficacy of Sulfasalazine in Pulmonary Arterial Hypertension. Trials, record NCT04528056. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04528056
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Pilot Study of the Safety and Efficacy of Sulfasalazine in Pulmonary Arterial Hypertension
- NCT number
- NCT04528056
- Status
- Unknown
- Phases
- Phase 1, Phase 2
- Enrollment
- 80 participants, estimated
- Lead sponsor
- RenJi Hospital
- Conditions
- Pulmonary Arterial Hypertension
- Interventions
- Sulfasalazine, Ambrisentan, Sulfasalazine's placebo, Ambrisentan's placebo
- First posted
- 2020-08-27
- Last updated
- 2020-08-27
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Time to First Confirmed Clinical Adverse Event up to the End of Treatment | Up to end of treatment (data presented up to month 6) | Clinical adverse event was defined as death. |
| Secondary | Change From Baseline to Month 6 in 6-minute Walk Distance | Baseline to month 6 | The 6-minute walk test (6MWT) is a non-encouraged test, performed in a 30 m long flat corridor, where the patient is instructed to walk as far as possible, back and forth around two cones, with the permission to slow down, rest, or stop if needed. These guidelines were provided to all sites. For patients who had never performed a 6MWT previously, a training test was required before the qualifying tests for inclusion were performed. |
| Secondary | Change From Baseline to Month 6 in Inflammation Factor | Baseline to month 6 | Compose of Interleukin-6 |
| Secondary | Change From Baseline to Month 6 in Echocardiography Examination | Baseline to month 6 | Assessment of pulmonary artery systolic pressure by echocardiography |
| Secondary | Change From Baseline to Month 6 in Cardiac Function | Baseline to month 6 | Compose of B-type natriuretic peptide |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04528056
GET https://conductscience.org/api/trials/v1/NCT04528056/registered