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Trial · NCT04543409

Results by group228

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Patients With a Histologic Response, Defined as a Peak Esophageal Intraepithelial Eosinophil Count ≤ 6 Eos/Hpf.BenralizumabWeek 2487.495% Confidence Interval 80.97 to 93.79Percentage of Participants
Percentage of Patients With a Histologic Response, Defined as a Peak Esophageal Intraepithelial Eosinophil Count ≤ 6 Eos/Hpf.PlaceboWeek 246.595% Confidence Interval 1.86 to 11.23Percentage of Participants
Percentage of Patients With a Histologic Response, Defined as a Peak Esophageal Intraepithelial Eosinophil Count ≤ 6 Eos/Hpf.BenralizumabWeek 5282.695% Confidence Interval 71.66 to 93.56Percentage of Participants
Percentage of Patients With a Histologic Response, Defined as a Peak Esophageal Intraepithelial Eosinophil Count ≤ 6 Eos/Hpf.PlaceboWeek 5289.495% Confidence Interval 80.55 to 98.18Percentage of Participants
Changes From Baseline in Dysphagia Symptom Questionnaire (DSQ)BenralizumabWeek 24-12.10295% Confidence Interval -16.05 to -8.15Score
Changes From Baseline in Dysphagia Symptom Questionnaire (DSQ)PlaceboWeek 24-15.10195% Confidence Interval -19.02 to -11.19Score
Changes From Baseline in Dysphagia Symptom Questionnaire (DSQ)BenralizumabWeek 52-19.40995% Confidence Interval -25.65 to -13.17Score
Changes From Baseline in Dysphagia Symptom Questionnaire (DSQ)PlaceboWeek 52-19.80695% Confidence Interval -25.70 to -13.91Score
Percent Change From Baseline in Tissue EosinophilsBenralizumabWeek 24-94.895% Confidence Interval -100.00 to -82.45Percentage of change
Percent Change From Baseline in Tissue EosinophilsPlaceboWeek 241.495% Confidence Interval -11.75 to 14.60Percentage of change
Percent Change From Baseline in Tissue EosinophilsBenralizumabWeek 52-85.095% Confidence Interval -100.00 to -62.50Percentage of change
Percent Change From Baseline in Tissue EosinophilsPlaceboWeek 52-88.695% Confidence Interval -100.00 to -73.67Percentage of change
Change From Baseline in Eosinophilic Esophagitis-Histology Scoring System (EoE-HSS) Total Grade Score at Week 24Benralizumab-0.26495% Confidence Interval -0.297 to -0.232Grade Score Ratio Change
Change From Baseline in Eosinophilic Esophagitis-Histology Scoring System (EoE-HSS) Total Grade Score at Week 24Placebo-0.08995% Confidence Interval -0.122 to -0.056Grade Score Ratio Change
Change From Baseline in Eosinophilic Esophagitis-Histology Scoring System (EoE-HSS) Total Stage Score at Week 24Benralizumab-0.19995% Confidence Interval -0.228 to -0.169Grade Score Ratio Change
Change From Baseline in Eosinophilic Esophagitis-Histology Scoring System (EoE-HSS) Total Stage Score at Week 24Placebo-0.07795% Confidence Interval -0.107 to -0.046Grade Score Ratio Change
Changes From Baseline in Centrally-read Endoscopic Reference Score (EREFS)BenralizumabWeek 24-0.595% Confidence Interval -0.91 to -0.10Score
Changes From Baseline in Centrally-read Endoscopic Reference Score (EREFS)PlaceboWeek 24-0.495% Confidence Interval -0.85 to -0.01Score
Changes From Baseline in Centrally-read Endoscopic Reference Score (EREFS)BenralizumabWeek 52-0.395% Confidence Interval -0.9 to 0.32Score
Changes From Baseline in Centrally-read Endoscopic Reference Score (EREFS)PlaceboWeek 52-0.795% Confidence Interval -1.35 to -0.09Score

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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