Self-regulation of Prefrontal Cortex During Emotional Cognitive Control
NCT04543500, Not applicable, Completed, Laureate Institute for Brain Research, Inc.
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Self-regulation of Prefrontal Cortex During Emotional Cognitive Control | ClinicalTrials.gov |
| NCT number | NCT04543500 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 70 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Laureate Institute for Brain Research, Inc. | ClinicalTrials.gov |
| Conditions | Healthy Volunteers, Cognitive Function | ClinicalTrials.gov |
| Interventions | Real-time functional magnetic resonance neurofeedback (rtfMRI-nf) | ClinicalTrials.gov |
| First posted | 2020-09-10 | ClinicalTrials.gov |
| Last updated | 2022-08-19 | ClinicalTrials.gov |
Registered outcomes 8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Left dorsolateral prefrontal cortex activity during emotional cognitive control (pre- to post-neurofeedback) | Approximately 2 hours after baseline assessment | Individual ability to regulate left dorsolateral prefrontal cortex activity during an emotional cognitive control task will be assessed before and after neurofeedback for both active and sham conditions. | ClinicalTrials.gov |
| Secondary | Left dorsolateral prefrontal cortex functional connectivity with other brain regions during rest (pre- to post-neurofeedback) | Approximately 2 hours after baseline assessment | Individual functional connectivity values between left dorsolateral prefrontal cortex and other brain regions during rest will be assessed before and after neurofeedback for both active and sham conditions. | ClinicalTrials.gov |
| Other | Emotional Stroop Average Reaction Time | Approximately 1 day after baseline assessment. | Average reaction time on the emotion condition of the emotional Stroop task. | ClinicalTrials.gov |
| Other | Color Word Stroop Average Reaction Time | Approximately 1 day after baseline assessment. | Average reaction time on the inhibition condition of the color word Stroop task. | ClinicalTrials.gov |
| Other | Flanker Task Average Reaction Time | Approximately 1 day after baseline assessment. | Average reaction time on the incongruent condition of the Flanker task. | ClinicalTrials.gov |
| Other | Emotional Stroop Reaction Time Difference | Approximately 1 day after baseline assessment. | Difference in reaction time for emotional versus neutral conditions of the emotional Stroop task. | ClinicalTrials.gov |
| Other | Color Word Stroop Reaction Time Difference | Approximately 1 day after baseline assessment. | Difference in reaction time for inhibition versus reading conditions of the emotional Stroop task. | ClinicalTrials.gov |
| Other | Flanker task Reaction Time Difference | Approximately 1 day after baseline assessment. | Difference in reaction time for incongruent versus congruent conditions of the Flanker task. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|---|---|---|---|---|---|
| F31MH122090 | Self-regulation of Prefrontal Cortex during Emotional Cognitive Control | MCDERMOTT, TIMOTHY | UNIVERSITY OF TULSA | NATIONAL INSTITUTE OF MENTAL HEALTH | 2020 to 2022 | NIH RePORTER |
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 3
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Emotional Stroop Task | Other outcome | ConductCognition |
| Eriksen Flanker Task | Other outcome | ConductCognition |
| Stroop Color-Word Test | Other outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)