Trial · NCT04545047
Observational Study of Convalescent Plasma for Treatment of Veterans With COVID-19
NCT04545047, Completed, VA Office of Research and Development; results first posted 2024-04-04
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Observational Study of Convalescent Plasma for Treatment of Veterans With COVID-19. Trials, record NCT04545047. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04545047
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Observational Study of Convalescent Plasma for Treatment of Veterans With COVID-19
- NCT number
- NCT04545047
- Status
- Completed
- Enrollment
- 5,044 participants, actual
- Lead sponsor
- VA Office of Research and Development
- Conditions
- Coronavirus Disease 2019 (COVID-19)
- Interventions
- COVID-19 convalescent plasma
- First posted
- 2020-09-10
- Last updated
- 2024-04-04
- Results first posted
- 2024-04-04
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | All-cause Mortality | 30 days | Death at 30 days recorded in the electronic health record. Follow-up starts at the treatment date, which must be within 2 days after both hospitalization and SARS-CoV-2-positive test, and ends at 30 days or death. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | All-cause Mortality | 30 days | Intention-to-treat analysis; per-protocol analysis with adjustment for baseline covariates via inverse probability weighting | Person-trials | COUNT_OF_UNITS |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| All-cause Mortality | Convalescent Plasma Group | 40 | Person-trials | ||
| All-cause Mortality | Non-plasma Group | 671 | Person-trials |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Exposed-Convalescent Plasma Group | 402 | 402 |
| Overall Study | STARTED | Unexposed-Non-Plasma Group | 4,642 | 10867 |
| Overall Study | COMPLETED | Exposed-Convalescent Plasma Group | 402 | 402 |
| Overall Study | COMPLETED | Unexposed-Non-Plasma Group | 4,642 | 10867 |
| Overall Study | NOT COMPLETED | Exposed-Convalescent Plasma Group | 0 | 0 |
| Overall Study | NOT COMPLETED | Unexposed-Non-Plasma Group | 0 | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Convalescent Plasma Group | 40 | 402 |
| Total, all-cause mortality | Non-plasma Group | 343 | 4,642 |
| Total, other adverse events | Convalescent Plasma Group | 0 | 0 |
| Total, other adverse events | Non-plasma Group | 0 | 0 |
| Total, serious adverse events | Convalescent Plasma Group | 0 | 0 |
| Total, serious adverse events | Non-plasma Group | 0 | 0 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 34153099 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Convalescent Plasma Group vs Non-plasma Group: deaths from any cause |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04545047
GET https://conductscience.org/api/trials/v1/NCT04545047/registered