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Trial · NCT04564339

Results by group80

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
IgAN Cohort: Percentage Change From Baseline in Proteinuria at Week 26 Measured by Absolute Protein (Based on 24-hour Urine Collections)IgAN Cohort: Ravulizumab-41.995% Confidence Interval -50.2 to -32.0percentage change
IgAN Cohort: Percentage Change From Baseline in Proteinuria at Week 26 Measured by Absolute Protein (Based on 24-hour Urine Collections)IgAN Cohort: Placebo-16.895% Confidence Interval -31.8 to 1.6percentage change
LN Cohort: Percentage Change From Baseline in Proteinuria at Week 26 Measured by Urine Protein to Creatinine Ratio (UPCR) (Based on 24-hour Urine Collections)LN Cohort: Ravulizumab-69.795% Confidence Interval -79.9 to -54.5percentage change
LN Cohort: Percentage Change From Baseline in Proteinuria at Week 26 Measured by Urine Protein to Creatinine Ratio (UPCR) (Based on 24-hour Urine Collections)LN Cohort: Placebo-67.095% Confidence Interval -80.8 to -43.1percentage change
IgAN Cohort: Percentage Change From Baseline in Proteinuria at Week 50 Measured by Absolute Protein (Based on 24-hour Urine Collections)IgAN Cohort - Ravulizumab-44.895% Confidence Interval -55.1 to -32.1percentage change
IgAN Cohort: Percentage Change From Baseline in Proteinuria at Week 50 Measured by Absolute Protein (Based on 24-hour Urine Collections)IgAN Cohort - Placebo-45.195% Confidence Interval -58.0 to -28.4percentage change
LN Cohort: Percentage Change From Baseline in Proteinuria at Week 50 Measured by UPCR (Based on 24-hour Urine Collections)LN Cohort: Ravulizumab-77.195% Confidence Interval -86.0 to -62.4percentage change
LN Cohort: Percentage Change From Baseline in Proteinuria at Week 50 Measured by UPCR (Based on 24-hour Urine Collections)LN Cohort: Placebo-75.095% Confidence Interval -87.2 to -51.2percentage change
IgAN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsIgAN Cohort: RavulizumabWeek 26: >30% Reduction68.395% Confidence Interval 51.9 to 81.9percentage of participants
IgAN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsIgAN Cohort: PlaceboWeek 26: >30% Reduction40.995% Confidence Interval 20.7 to 63.6percentage of participants
IgAN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsIgAN Cohort: RavulizumabWeek 26: >50% Reduction43.995% Confidence Interval 28.5 to 60.3percentage of participants
IgAN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsIgAN Cohort: PlaceboWeek 26: >50% Reduction18.295% Confidence Interval 5.2 to 40.3percentage of participants
IgAN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsIgAN Cohort: RavulizumabWeek 50: >30% Reduction63.495% Confidence Interval 46.9 to 77.9percentage of participants
IgAN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsIgAN Cohort: PlaceboWeek 50: >30% Reduction60.995% Confidence Interval 38.5 to 80.3percentage of participants
IgAN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsIgAN Cohort: RavulizumabWeek 50: >50% Reduction36.695% Confidence Interval 22.1 to 53.1percentage of participants
IgAN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsIgAN Cohort: PlaceboWeek 50: >50% Reduction39.195% Confidence Interval 19.7 to 61.5percentage of participants
LN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsLN Cohort: RavulizumabWeek 26: >30% Reduction50.095% Confidence Interval 33.4 to 66.6percentage of participants
LN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsLN Cohort: PlaceboWeek 26: >30% Reduction73.795% Confidence Interval 48.8 to 90.9percentage of participants
LN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsLN Cohort: RavulizumabWeek 26: >50% Reduction47.495% Confidence Interval 31.0 to 64.2percentage of participants
LN Cohort: Percentage of Participants With > 30% and > 50% Reduction in Proteinuria at Week 26 and Week 50 Compared to Baseline Assessed Using 24-hour Urine CollectionsLN Cohort: PlaceboWeek 26: >50% Reduction57.995% Confidence Interval 33.5 to 79.7percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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