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Trial · NCT04568434

Results by group48

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change From Baseline in Fasting TG at Month 6Placebo11.5295% Confidence Interval -5.321 to 28.356percent change
Percent Change From Baseline in Fasting TG at Month 6Olezarsen 50 mg-10.8595% Confidence Interval -27.797 to 6.095percent change
Percent Change From Baseline in Fasting TG at Month 6Olezarsen 80 mg-31.9995% Confidence Interval -49.031 to -14.940percent change
Percent Change From Baseline in Fasting TG at Month 12Placebo20.8995% Confidence Interval 1.016 to 40.764percent change
Percent Change From Baseline in Fasting TG at Month 12Olezarsen 50 mg-22.9295% Confidence Interval -42.505 to -3.336percent change
Percent Change From Baseline in Fasting TG at Month 12Olezarsen 80 mg-38.5095% Confidence Interval -58.187 to -18.815percent change
Percent Change From Baseline in Fasting Apolipoprotein C-III (apoC-III) at Months 6 and 12PlaceboMonth 67.5795% Confidence Interval -5.229 to 20.359percent change
Percent Change From Baseline in Fasting Apolipoprotein C-III (apoC-III) at Months 6 and 12Olezarsen 50 mgMonth 6-57.9195% Confidence Interval -71.193 to -44.631percent change
Percent Change From Baseline in Fasting Apolipoprotein C-III (apoC-III) at Months 6 and 12Olezarsen 80 mgMonth 6-66.1395% Confidence Interval -79.437 to -52.823percent change
Percent Change From Baseline in Fasting Apolipoprotein C-III (apoC-III) at Months 6 and 12PlaceboMonth 1217.0895% Confidence Interval 2.149 to 32.009percent change
Percent Change From Baseline in Fasting Apolipoprotein C-III (apoC-III) at Months 6 and 12Olezarsen 50 mgMonth 12-59.9895% Confidence Interval -75.163 to -44.795percent change
Percent Change From Baseline in Fasting Apolipoprotein C-III (apoC-III) at Months 6 and 12Olezarsen 80 mgMonth 12-64.2095% Confidence Interval -79.408 to -48.984percent change
Percentage of Participants With ≥ 40% Reduction in Fasting TG at Month 6Placebo4.3percentage of participants
Percentage of Participants With ≥ 40% Reduction in Fasting TG at Month 6Olezarsen 50 mg33.3percentage of participants
Percentage of Participants With ≥ 40% Reduction in Fasting TG at Month 6Olezarsen 80 mg40.9percentage of participants
Percent Change From Baseline in Fasting Apolipoprotein B-48 (apoB-48) at Months 6 and 12PlaceboMonth 624.5095% Confidence Interval -9.972 to 58.973percent change
Percent Change From Baseline in Fasting Apolipoprotein B-48 (apoB-48) at Months 6 and 12Olezarsen 50 mgMonth 6-8.7895% Confidence Interval -42.976 to 25.406percent change
Percent Change From Baseline in Fasting Apolipoprotein B-48 (apoB-48) at Months 6 and 12Olezarsen 80 mgMonth 6-59.4695% Confidence Interval -93.164 to -25.765percent change
Percent Change From Baseline in Fasting Apolipoprotein B-48 (apoB-48) at Months 6 and 12PlaceboMonth 12-3.5295% Confidence Interval -53.159 to 46.124percent change
Percent Change From Baseline in Fasting Apolipoprotein B-48 (apoB-48) at Months 6 and 12Olezarsen 50 mgMonth 12-36.4195% Confidence Interval -77.689 to 4.860percent change

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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