Trial · NCT04573023
A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT)
NCT04573023, Phase 3, Active not recruiting, JCR Pharmaceuticals Co., Ltd.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT). Trials, record NCT04573023. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04573023
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT)
- NCT number
- NCT04573023
- Status
- Active not recruiting
- Phases
- Phase 3
- Enrollment
- 86 participants, actual
- Lead sponsor
- JCR Pharmaceuticals Co., Ltd.
- Conditions
- Mucopolysaccharidosis II
- Interventions
- JR-141, Idursulfase, JR-141 or Idursulfase
- First posted
- 2020-10-05
- Last updated
- 2026-10-02
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in levels of cerebrospinal fluid heparan sulfate from baseline (Cohort A) | Baseline to Week 53 | |
| Primary | Change in the raw scores of cognitive testing measured from baseline (BSID-III) (Cohort A) | Baseline to Week 105 | |
| Secondary | For regions other than US: Change in the age equivalent scores of cognitive testing measured from baseline (BSID-III or KABC-II) (Cohort A) | Baseline to Week 105 | |
| Secondary | For regions other than US: Change in the age equivalent scores of adaptive behavior measured from baseline (VABS-II) (Cohort A) | Baseline to Week 105 | |
| Secondary | For the US: Change in the raw scores of adaptive behavior measured from baseline (VABS-II) (Cohort A) | Baseline to Week 105 | |
| Secondary | For all regions: Relative change in liver volume relative to body weight from baseline (Cohort A and Cohort B) | Baseline to Week 53 | |
| Secondary | For all regions: Relative change in spleen volume relative to body weight from baseline (Cohort A and Cohort B) | Baseline to Week 53 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04573023
GET https://conductscience.org/api/trials/v1/NCT04573023/registered