Trial · NCT04573920
Atrasentan in Patients With Proteinuric Glomerular Diseases
NCT04573920, Phase 2, Active not recruiting, Novartis Pharmaceuticals
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Atrasentan in Patients With Proteinuric Glomerular Diseases. Trials, record NCT04573920. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04573920
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Atrasentan in Patients With Proteinuric Glomerular Diseases
- NCT number
- NCT04573920
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 103 participants, actual
- Lead sponsor
- Novartis Pharmaceuticals
- Conditions
- IgA Nephropathy, Focal Segmental Glomerulosclerosis, Alport Syndrome, Diabetic Kidney Disease, Diabetic Nephropathy Type 2, Immunoglobulin A Nephropathy
- Interventions
- Atrasentan
- First posted
- 2020-10-05
- Last updated
- 2026-06-01
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in proteinuria for IgAN, FSGS, and Alport syndrome patients receiving 0.75 mg atrasentan QD | Up to Week 12 or approximately 3 months | The change in urine protein:creatinine ratio (UPCR) from baseline to Week 12 |
| Primary | Change in albuminuria for DKD patients | Up to Week 12 or approximately 3 months | The change in urine albumin:creatinine ratio (UACR) from baseline to Week 12 |
| Primary | Change in proteinuria for FSGS patients at 1.5 mg dose | Up to Week 24 or approximately 6 months | The change in urine protein:creatinine ratio (UPCR) from baseline to Week 24 |
| Primary | Change in proteinuria for FSGS patients at 1.5 mg dose | Up to Week 30 or approximately 7.5 months | The change in urine protein:creatinine ratio (UPCR) from baseline to Week 30 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04573920
GET https://conductscience.org/api/trials/v1/NCT04573920/registered