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CRISIS2: A Phase 2 Study of the Safety and Antiviral Activity of Brequinar in Non-hospitalized Pts With COVID-19
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Trial · NCT04575038

Results by group38

Each measurement the trial posted, group by group, in the words and numbers it posted.

1 to 20 of 38

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OutcomeGroupCategoryValueSpreadUnits
Log10 SARS-CoV-2 Viral LoadStandard of Care + Brequinar 100 mgBaseline5.056Full Range 3.14 to 7.96Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + PlaceboBaseline5.110Full Range 3.14 to 8.22Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + Brequinar 100 mgDay 4 Change from Baseline-1.651Full Range -7.94 to 0.87Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + PlaceboDay 4 Change from Baseline-1.881Full Range -7.21 to 0.93Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + Brequinar 100 mgDay 8 Change from Baseline-2.413Full Range -7.94 to 1.85Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + PlaceboDay 8 Change from Baseline-3.231Full Range -7.78 to 0.12Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + Brequinar 100 mgDay 12 Change from Baseline-3.907Full Range -7.94 to 0.45Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + PlaceboDay 12 Change from Baseline-3.514Full Range -7.78 to 0.00Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + Brequinar 100 mgDay 15 Change from Baseline-4.140Full Range -7.94 to 0.20Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + PlaceboDay 15 Change from Baseline-3.143Full Range -7.78 to 1.40Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + Brequinar 100 mgDay 22 Change from Baseline-4.874Full Range -7.94 to 0.26Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + PlaceboDay 22 Change from Baseline-3.575Full Range -7.78 to -0.31Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + Brequinar 100 mgDay 29 Change from Baseline-4.170Full Range -7.94 to 3.09Log 10 SARS-CoV-2 Viral Load Copies/mL
Log10 SARS-CoV-2 Viral LoadStandard of Care + PlaceboDay 29 Change from Baseline-3.839Full Range -7.78 to -1.20Log 10 SARS-CoV-2 Viral Load Copies/mL
Rates of AEs and SAEs Including Laboratory AssessmentsStandard of Care + Brequinar 100 mgAny AE10Participants
Rates of AEs and SAEs Including Laboratory AssessmentsStandard of Care + PlaceboAny AE13Participants
Rates of AEs and SAEs Including Laboratory AssessmentsStandard of Care + Brequinar 100 mgMaximum Grade 1 AE8Participants
Rates of AEs and SAEs Including Laboratory AssessmentsStandard of Care + PlaceboMaximum Grade 1 AE8Participants
Rates of AEs and SAEs Including Laboratory AssessmentsStandard of Care + Brequinar 100 mgMaximum Grade 2 AE1Participants
Rates of AEs and SAEs Including Laboratory AssessmentsStandard of Care + PlaceboMaximum Grade 2 AE2Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT04575038/results

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