Trial · NCT04575610
Registered outcomes25
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 20 of 25
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | All-cause mortality at Day 29 | Up to 29 days | All-cause mortality at Day 29 (end of planned treatment period). |
| Secondary | Disease Severity (8 point scale) | 29 days | Proportion of patients alive, extubated, and receiving no more than low flow oxygen supplementation by nasal cannula or face mask (excluding extubation for compassionate purposes in terminal patients). This would correspond to an at least 2 point decrease in the NIAID ordinal scale. The NIAID scale is as follows: 1. Not hospitalized, no limitations on activities 2. Not hospitalized, limitations on activities and/or requiring home oxygen 3. Hospitalized, not requiring supplemental oxygen - no longer requires ongoing medical care 4. Hospitalized, not requiring supplemental oxygen - requiring ongoing medical care (COVID-19 related or otherwise) 5. Hospitalized, requiring supplemental oxygen 6. Hospitalized, on non-invasive ventilation or high-flow oxygen devices 7. Hospitalized, on invasive mechanical ventilation or ECMO 8. Death |
| Secondary | Disease Severity (8 point scale) | 61 days | Proportion of patients alive, extubated, and receiving no more than low flow oxygen supplementation by nasal cannula or face mask (excluding extubation for compassionate purposes in terminal patients). This would correspond to an at least 2 point decrease in the NIAID ordinal scale (1 = not hospitalized, no limitations on activities, and 8 = death) at Day 61. |
| Secondary | Disease Severity (8 point scale) | 29 days | Proportion of patients alive, extubated, and receiving any level oxygen supplementation, including non-invasive positive pressure ventilation or high flow oxygen device (excluding extubation for compassionate purposes in terminal patients). This would correspond to an at least 1-point decrease in the NIAID ordinal scale (1 = not hospitalized, no limitations on activities, and 8 = death) at Day 29. |
| Secondary | Disease Severity (8 point scale) | 61 days | Proportion of patients alive, extubated, and receiving any level oxygen supplementation, including non-invasive positive pressure ventilation or high flow oxygen device (excluding extubation for compassionate purposes in terminal patients). This would correspond to an at least 1-point decrease in the NIAID ordinal scale (1 = not hospitalized, no limitations on activities, and 8 = death) at Day 61. |
| Secondary | Disease Severity (8 point scale) | 8 days | Percentage of patients in each category of the NIAID 8-point ordinal scale of disease severity at Day 8. The ordinal scale is an assessment of the clinical status at the first assessment of a given study day in which 1 = not hospitalized, no limitations on activities, and 8 = death. |
| Secondary | Disease Severity (8 point scale) | 15 days | Percentage of patients in each category of the NIAID 8-point ordinal scale of disease severity at Day 15. The ordinal scale is an assessment of the clinical status at the first assessment of a given study day in which 1 = not hospitalized, no limitations on activities, and 8 = death. |
| Secondary | Disease Severity (8 point scale) | 22 days | Percentage of patients in each category of the NIAID 8-point ordinal scale of disease severity at Day 22. The ordinal scale is an assessment of the clinical status at the first assessment of a given study day in which 1 = not hospitalized, no limitations on activities, and 8 = death. |
| Secondary | Disease Severity (8 point scale) | 29 days | Percentage of patients in each category of the NIAID 8-point ordinal scale of disease severity at Day 29. The ordinal scale is an assessment of the clinical status at the first assessment of a given study day in which 1 = not hospitalized, no limitations on activities, and 8 = death. |
| Secondary | Disease Severity (8 point scale) | 61 days | Percentage of patients in each category of the NIAID 8-point ordinal scale of disease severity at Day 61. The ordinal scale is an assessment of the clinical status at the first assessment of a given study day in which 1 = not hospitalized, no limitations on activities, and 8 = death. |
| Secondary | Mortality | 61 days | Mortality rate at day 61 |
| Secondary | Disease Severity (8 point scale) | 29 days | Time to a 1-point decrease in the NIAID 8-point ordinal scale of disease severity (1 = not hospitalized, no limitations on activities, and 8 = death). |
| Secondary | Disease Severity (8 point scale) | 29 days | Time to a 2-point decrease in the NIAID 8-point ordinal scale of disease severity. |
| Secondary | Disease Severity (8 point scale) | 3 days | Change from baseline in the ordinal scale from Day 1 to Days 3. |
| Secondary | Disease Severity (8 point scale) | 5 days | Change from baseline in the ordinal scale from Day 1 to Days 5. |
| Secondary | Disease Severity (8 point scale) | 8 days | Change from baseline in the ordinal scale from Day 1 to Days 8. |
| Secondary | Disease Severity (8 point scale) | 11 days | Change from baseline in the ordinal scale from Day 1 to Days 11. |
| Secondary | Disease Severity (8 point scale) | 15 days | Change from baseline in the ordinal scale from Day 1 to Days 15. |
| Secondary | Disease Severity (8 point scale) | 22 days | Change from baseline in the ordinal scale from Day 1 to Days 22. |
| Secondary | Disease Severity (8 point scale) | 29 days | Change from baseline in the ordinal scale from Day 1 to Days 29. |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT04575610/registered