Trial · NCT04591353
Trial Comparing Impact of PENG Block on Quality of Recovery Compared to No-block for Primary Total Hip Arthroplasty
NCT04591353, Phase 3, Completed, University of Alabama at Birmingham; results first posted 2023-02-17
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Trial Comparing Impact of PENG Block on Quality of Recovery Compared to No-block for Primary Total Hip Arthroplasty. Trials, record NCT04591353. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04591353
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Trial Comparing Impact of PENG Block on Quality of Recovery Compared to No-block for Primary Total Hip Arthroplasty
- NCT number
- NCT04591353
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 122 participants, actual
- Lead sponsor
- University of Alabama at Birmingham
- Conditions
- Total Hip Arthroplasty
- Interventions
- PENG Block, Lidocaine
- First posted
- 2020-10-19
- Last updated
- 2024-02-15
- Results first posted
- 2023-02-17
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Recovery After Total Hip Arthroplasty | 24 hours after surgery | The quality of recovery-15 is a validated questionnaire to assess postoperative recovery. I Scale is based on 15 questions, each question score range is 0-10 (0 being poor and 10 being excellent) The survey will be conducted at 24 hours after surgery Total score range is 0-150, where a score of 0 would be the worst possible score, and 150 would be the best possible score. |
| Secondary | Evaluating Recovery After Total Hip Arthroplasty | 2 days after surgery | Quality of recovery (QoR) survey at 48 hours after surgery. QoR-15 scores range from 0 (extremely poor quality of recovery) to 150 (excellent quality of recovery). |
| Secondary | Average Pain Medicine Required After Surgery. | 24 and 48 hours after surgery | Measuring the average milligrams of oral morphine equivalent (OME) consumption at 24 and 48 hours after surgery |
| Secondary | Pain Scores After Surgery | Recovery (PACU), 6, 12, 24 and 48 hours after surgery | Pain scores (visual analog scores VAS) in recovery (PACU), 6, 12, 24 and 48 hours after surgery |
| Secondary | Ambulation Distance After Surgery | 24 and 48 hours after surgery | ambulation distance as recorded by physical therapist at 24 and 48 hours after surgery |
| Secondary | Total Patients Using Antiemetics After Surgery | up to 2 days after surgery | use of any medication for nausea or vomiting prevention after surgery |
Source ClinicalTrials.gov
Outcomes6
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Recovery After Total Hip Arthroplasty | 24 hours after surgery | score on a scale | MEDIAN | |
| SECONDARY | Evaluating Recovery After Total Hip Arthroplasty | 2 days after surgery | score on a scale | MEDIAN | |
| SECONDARY | Average Pain Medicine Required After Surgery. | 24 and 48 hours after surgery | Milligrams | MEAN | |
| SECONDARY | Pain Scores After Surgery | Recovery (PACU), 6, 12, 24 and 48 hours after surgery | score on a scale | MEAN | |
| SECONDARY | Ambulation Distance After Surgery | 24 and 48 hours after surgery | feet | MEAN | |
| SECONDARY | Total Patients Using Antiemetics After Surgery | up to 2 days after surgery | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group24
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Recovery After Total Hip Arthroplasty | Investigational Group (PENG Block Group) | 131.5 | Full Range 116 to 138 | score on a scale | |
| Recovery After Total Hip Arthroplasty | Control Group | 103 | Full Range 97 to 111 | score on a scale | |
| Evaluating Recovery After Total Hip Arthroplasty | Investigational Group (PENG Block Group) | 136 | Inter-Quartile Range 22.5 to 143 | score on a scale | |
| Evaluating Recovery After Total Hip Arthroplasty | Control Group | 108 | Inter-Quartile Range 100 to 119.5 | score on a scale | |
| Average Pain Medicine Required After Surgery. | Investigational Group (PENG Block Group) | 24 hour | 37.3 | Standard Deviation 29.7 | Milligrams |
| Average Pain Medicine Required After Surgery. | Control Group | 24 hour | 59.5 | Standard Deviation 43.4 | Milligrams |
| Average Pain Medicine Required After Surgery. | Investigational Group (PENG Block Group) | 48hour | 47.1 | Standard Deviation 40.5 | Milligrams |
| Average Pain Medicine Required After Surgery. | Control Group | 48hour | 75.4 | Standard Deviation 57.8 | Milligrams |
| Pain Scores After Surgery | Investigational Group (PENG Block Group) | PACU | 1.8 | Standard Deviation 1.5 | score on a scale |
| Pain Scores After Surgery | Control Group | PACU | 2.3 | Standard Deviation 1.7 | score on a scale |
1 to 10 of 24Source ClinicalTrials.gov
See all 24 results by groupParticipant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Investigational Group (PENG Block Group) | 61 | |
| Overall Study | STARTED | Control Group | 61 | |
| Overall Study | COMPLETED | Investigational Group (PENG Block Group) | 56 | |
| Overall Study | COMPLETED | Control Group | 56 | |
| Overall Study | NOT COMPLETED | Investigational Group (PENG Block Group) | 5 | |
| Overall Study | NOT COMPLETED | Control Group | 5 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Investigational Group (PENG Block Group) | 0 | 56 |
| Total, all-cause mortality | Control Group | 0 | 56 |
| Total, other adverse events | Investigational Group (PENG Block Group) | 0 | 56 |
| Total, other adverse events | Control Group | 0 | 56 |
| Total, serious adverse events | Investigational Group (PENG Block Group) | 0 | 56 |
| Total, serious adverse events | Control Group | 0 | 56 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 36964012 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons3
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Investigational Group (PENG Block Group) vs Control Group: Total Patients Using Antiemetics After Surgery | Trial comparisons |
| Investigational Group (PENG Block Group) vs Control Group: deaths from any cause | Trial comparisons |
| Investigational Group (PENG Block Group) vs Control Group: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04591353
GET https://conductscience.org/api/trials/v1/NCT04591353/results?page=2