Trial · NCT04593654
Dosing of Thromboprophylaxis and Mortality in Critically Ill COVID-19 Patients
NCT04593654, Completed, Karolinska Institutet
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Dosing of Thromboprophylaxis and Mortality in Critically Ill COVID-19 Patients. Trials, record NCT04593654. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04593654
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Dosing of Thromboprophylaxis and Mortality in Critically Ill COVID-19 Patients
- NCT number
- NCT04593654
- Status
- Completed
- Enrollment
- 257 participants, actual
- Lead sponsor
- Karolinska Institutet
- Conditions
- Covid19, Thromboembolism
- Interventions
- Dose of tinzaparin or dalteparin
- First posted
- 2020-10-20
- Last updated
- 2023-05-31
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 28-day mortality | 28 days from ICU-admission | 28-day mortality from admission to ICU. Discontinue of ICU-care to palliative care counts as death. |
| Secondary | Incidence of thromboembolic events | 28 days from ICU-admission | Thromboembolic events are defined as pulmonary emboli (PE), deep venous thrombus (DVT) and ischemic stroke. PE is defined as PE verified by computer tomography or by findings of acute strain of the right heart on echocardiography combined with a clinical interpretation of the patients deteriorating as a probable PE stated in the medical records. DVT is defined as DVT verified with ultrasound. Ischemic stroke is defined as ischemic stroke verified by computer tomography. |
| Secondary | Incidence of bleeding events | 28 days from ICU-admission | The event of bleeding will be defined by WHO modified bleeding scale as 1-4 |
| Secondary | ICU-free days alive from ICU-admission | 28 days from ICU-admission | ICU-free days alive during 28 days from ICU-admission. Counts as 0 days if discharged to ward for palliative treatment. |
| Secondary | 90-day mortality | 90 days from ICU-admission | 90-day mortality from admission to ICU. |
| Other | Fibrin-D-dimer levels | 28 days from ICU-admission | Median value of Fibrin-D-dimer |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 34875111 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04593654
GET https://conductscience.org/api/trials/v1/NCT04593654/registered