Trial · NCT04627025
Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF
NCT04627025, Phase 3, Completed, VectivBio AG
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF. Trials, record NCT04627025. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04627025
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF
- NCT number
- NCT04627025
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 164 participants, actual
- Lead sponsor
- VectivBio AG
- Conditions
- Short Bowel Syndrome
- Interventions
- apraglutide
- First posted
- 2020-11-13
- Last updated
- 2024-11-27
- Other registries' IDs
- eudract:2020-001202-32
Source ClinicalTrials.gov
Registered outcomes16
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Relative change from baseline in actual weekly PS volume at Week 24. | At week 24 of treatment | |
| Secondary | Subjects who achieve a reduction of at least 1 day per week of PS at Weeks 24 / 48 (CIC only). | Weeks 24 and 48 of treatment | |
| Secondary | Relative change from baseline in actual weekly PS volume at Weeks 12 / 24 / 48 (CIC only). | Weeks 12 / 24 / 48 of treatment | |
| Secondary | Subjects reaching enteral autonomy at Weeks 24 / 48 (CIC only). | Weeks 24 / 48 of treatment | |
| Secondary | At least 20% reduction of PS volume from baseline at Weeks 20 / 24. | Weeks 20 / 24 of treatment | |
| Secondary | Calorie reduction in the PN at Weeks 24. | Weeks 24 of treatment | |
| Secondary | Change from baseline on the Pittsburgh Sleep Quality Inventory (PSQI) at Weeks 24 / 48 (CIC only) | Weeks 24 / 48 of treatment | |
| Secondary | Change from baseline on the Patient Global Impression of Change (PGIC) at Weeks 24 / 48 (CIC only) | Weeks 24 / 48 of treatment. | |
| Secondary | Change from baseline on the Patient Global Impression of Treatment Satisfaction (PGI-TS) at week 24 and 48 (CIC only). | Weeks 24 / 48 of treatment | |
| Secondary | Change from baseline on the Patient Global Impression of Satisfaction with Parenteral Support (PGI-SPS) at Week 24 and 48 (CIC only). | Weeks 24 / 48 of treatment |
1 to 10 of 16Source ClinicalTrials.gov
See all 16 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04627025
GET https://conductscience.org/api/trials/v1/NCT04627025/registered