Trial · NCT04631484
International Trial of Efficacy of Cytoflavin in Head Trauma
NCT04631484, Phase 3, Completed, POLYSAN Scientific & Technological Pharmaceutical Company
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. International Trial of Efficacy of Cytoflavin in Head Trauma. Trials, record NCT04631484. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04631484
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- International Trial of Efficacy of Cytoflavin in Head Trauma
- NCT number
- NCT04631484
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 166 participants, actual
- Lead sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
- Conditions
- Head Trauma,Closed
- Interventions
- Cytoflavin ((Inosine + Nicotinamide + Riboflavin + Succinic Acid), Placebo
- First posted
- 2020-11-17
- Last updated
- 2025-04-18
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Galveston Orientation and Amnesia scale | 7 days | The proportion of patients with regression of post-traumatic amnesia by day 7 of treatment, defined as having a Galveston score of \>75 points on 3 consecutive days, up to and including day 7 of treatment. |
| Primary | Glasgow Outcome scale - Extended (GOS-E) | 90 days | Assessment by GOS-E after 3 months |
| Secondary | Glasgow Coma Scale | 14 days | Daily assessment by GCS for the period up to 14 days of the study |
| Secondary | Barthel Index | 14 days | Assessement of Barthel Activities of daily living Index on day 14 or discharge, whatever earlier |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 41551305 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04631484
GET https://conductscience.org/api/trials/v1/NCT04631484/registered