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Trial · NCT04639310

Results by group32

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change From Baseline in Monthly (28 Day) Countable Motor Seizure Frequency During the Blinded Treatment PeriodXEN496-46.0Standard Deviation 23.49percentage change from baseline
Percent Change From Baseline in Monthly (28 Day) Countable Motor Seizure Frequency During the Blinded Treatment PeriodPlacebo25.6Standard Deviation 46.84percentage change from baseline
Percentage of Subjects With ≥50 Percent Reduction in Monthly (28 Day) Seizure FrequencyXEN4962Participants
Percentage of Subjects With ≥50 Percent Reduction in Monthly (28 Day) Seizure FrequencyPlacebo0Participants
Caregiver Global Impression of Change (CaGI-C) Scores for the Subject's Overall Condition and for SeizuresXEN496Overall Condition1Participants
Caregiver Global Impression of Change (CaGI-C) Scores for the Subject's Overall Condition and for SeizuresPlaceboOverall Condition1Participants
Caregiver Global Impression of Change (CaGI-C) Scores for the Subject's Overall Condition and for SeizuresXEN496Seizure Severity1Participants
Caregiver Global Impression of Change (CaGI-C) Scores for the Subject's Overall Condition and for SeizuresPlaceboSeizure Severity1Participants
Change From Baseline in the Caregiver Global Impression of Severity (CaGI-S) for the Subject's Overall Condition and for SeizuresXEN496Overall Condition0Participants
Change From Baseline in the Caregiver Global Impression of Severity (CaGI-S) for the Subject's Overall Condition and for SeizuresPlaceboOverall Condition1Participants
Change From Baseline in the Caregiver Global Impression of Severity (CaGI-S) for the Subject's Overall Condition and for SeizuresXEN496Seizure Severity1Participants
Change From Baseline in the Caregiver Global Impression of Severity (CaGI-S) for the Subject's Overall Condition and for SeizuresPlaceboSeizure Severity0Participants
Safety and Tolerability of XEN496 (e.g., Adverse Events) in Pediatric Subjects With KCNQ2-DEEXEN496No. of Subject with any AE5Participants
Safety and Tolerability of XEN496 (e.g., Adverse Events) in Pediatric Subjects With KCNQ2-DEEPlaceboNo. of Subject with any AE3Participants
Safety and Tolerability of XEN496 (e.g., Adverse Events) in Pediatric Subjects With KCNQ2-DEEXEN496No. of Subjects with any TEAE5Participants
Safety and Tolerability of XEN496 (e.g., Adverse Events) in Pediatric Subjects With KCNQ2-DEEPlaceboNo. of Subjects with any TEAE3Participants
Safety and Tolerability of XEN496 (e.g., Adverse Events) in Pediatric Subjects With KCNQ2-DEEXEN496No. of Subjects with any Treatment Related TEAE1Participants
Safety and Tolerability of XEN496 (e.g., Adverse Events) in Pediatric Subjects With KCNQ2-DEEPlaceboNo. of Subjects with any Treatment Related TEAE0Participants
Safety and Tolerability of XEN496 (e.g., Adverse Events) in Pediatric Subjects With KCNQ2-DEEXEN496No. of Subjects with any TEAE leading to discontinuation of study drug0Participants
Safety and Tolerability of XEN496 (e.g., Adverse Events) in Pediatric Subjects With KCNQ2-DEEPlaceboNo. of Subjects with any TEAE leading to discontinuation of study drug0Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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