Trial · NCT04675762
Combinating Fingolimod With Alteplase Bridging With Thrombectomy in Acute Ischemic Stroke
NCT04675762, Phase 2, Unknown, Second Affiliated Hospital, Zhejiang University, School of Medicine
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Combinating Fingolimod With Alteplase Bridging With Thrombectomy in Acute Ischemic Stroke. Trials, record NCT04675762. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04675762
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Combinating Fingolimod With Alteplase Bridging With Thrombectomy in Acute Ischemic Stroke
- NCT number
- NCT04675762
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 118 participants, estimated
- Lead sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
- Conditions
- Stroke, Inflammation
- Interventions
- Fingolimod, Placebo
- First posted
- 2020-12-19
- Last updated
- 2023-04-18
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | independent recovery assessed by ratio of modefied Rankin Scale (mRS) score of 0-2 (%) | at 90 day | mRS: minimum value = 0, maximum value = 6, and lower scores mean a better outcome |
| Secondary | salvaged ischemic tissue index (%) | from baseline to 7 day | 100\*(baseline CTP ischemic lesion (mL) - 7 day DWI infarction lesion (mL))/ baseline CTP ischemic lesion (mL) |
| Secondary | the growth in infarct volume (mL) | from 24 hour to 7 day | 24 hour DWI infarct volume (mL) - 7 day DWI infarct volume (mL) |
| Secondary | the penumbral salvage volume (mL) | from baseline to 1 day | (baseline CTP hypoperfusion volume (mL) - 24 hour DWI infarct volume (mL)) |
| Secondary | the frequency of parenchymal hemorrhage (PH) (%) | at day 1 | the presence of PH is defined according the standard from ECASS-2 study |
| Secondary | the change on the National Institute of Health stroke scale (NIHSS) score from baseline to 1 day | from baseline to 1 day | NIHSS: minimum value = 0, maximum value = 42, and higher scores mean severer symptoms |
| Secondary | the change on the National Institute of Health stroke scale (NIHSS) score from baseline to 7 day | from baseline to 7 day | NIHSS: minimum value = 0, maximum value = 42, and higher scores mean severer symptoms |
| Secondary | excellent recovery assessed by the ratio of modefied Rankin Scale (mRS) score of 0-1 (%) | at day 90 | mRS: minimum value = 0, maximum value = 6, and lower scores mean a better outcome |
| Secondary | general recovery assessed by the ratio of modefied Rankin Scale (mRS) score of 0-3 (%) | at day 90 | mRS: minimum value = 0, maximum value = 6, and lower scores mean a better outcome |
| Secondary | recovery assessed by modefied Rankin Scale (mRS) score | at day 90 | mRS: minimum value = 0, maximum value = 6, and lower scores mean a better outcome |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04675762
GET https://conductscience.org/api/trials/v1/NCT04675762/registered