Neuropsychiatry and Cognition in SCA3/MJD
NCT04714307, Unknown, Hospital de Clinicas de Porto Alegre
Trial 9
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Neuropsychiatry and Cognition in SCA3/MJD | ClinicalTrials.gov |
| NCT number | NCT04714307 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Enrollment | 144 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Hospital de Clinicas de Porto Alegre | ClinicalTrials.gov |
| Conditions | Spinocerebellar Ataxia Type 3, Machado-Joseph Disease, SCA3, MJD | ClinicalTrials.gov |
| Interventions | SCA3/MJD molecular diagnosis, Cognitive Testing, Psychiatric Evaluation, Clinical Neurological Evaluation, Emotional Attribution Evaluation, Activities of Daily Living | ClinicalTrials.gov |
| First posted | 2021-01-19 | ClinicalTrials.gov |
| Last updated | 2021-01-19 | ClinicalTrials.gov |
Registered outcomes 11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Cerebellar Cognitive Affective Syndrome Scale | Through study completion, an average of 1 year | Study the performance on the Cerebellar Cognitive Affective Syndrome Scale of SCA3/MJD symptomatic subjects when compared to matched healthy controls and of pre-symptomatic subjects when compared to familial healthy controls. | ClinicalTrials.gov |
| Primary | Trail-Making Test Part A and B | Through study completion, an average of 1 year | Study the performance on the Trail-Making Test Part A and B of SCA3/MJD symptomatic subjects when compared to matched healthy controls and of pre-symptomatic subjects when compared to familial healthy controls. | ClinicalTrials.gov |
| Primary | Stroop Color-Word Test | Through study completion, an average of 1 year | Study the performance on the Stroop Color-Word Test of SCA3/MJD symptomatic subjects when compared to matched healthy controls and of pre-symptomatic subjects when compared to familial healthy controls. | ClinicalTrials.gov |
| Primary | Emotion Attribution impairment in SCA3/MJD | Through study completion, an average of 1 year | Study the performance of symptomatic SCA3/MJD carriers in the Reading the Mind in the Eyes Test. | ClinicalTrials.gov |
| Primary | Emotion Attribution in different phases of the disease | Through study completion, an average of 1 year | Study the performance of pre-symptomatic SCA3/MJD carriers in the Reading the Mind in the Eyes Test. | ClinicalTrials.gov |
| Primary | Hamilton Anxiety Rating Scale | Through study completion, an average of 1 year | Study the profile of symptomatic and pre-symptomatic SCA3/MJD carriers in the Hamilton Anxiety Rating Scale. | ClinicalTrials.gov |
| Primary | Hamilton Depression Rating Scale | Through study completion, an average of 1 year | Study the profile of symptomatic and pre-symptomatic SCA3/MJD carriers in the Hamilton Depression Rating Scale. | ClinicalTrials.gov |
| Secondary | Scale for the Assessment and Rating of Ataxia (SARA) | Through study completion, an average of 1 year | Correlations between primary outcomes and SARA. | ClinicalTrials.gov |
| Secondary | Composite Cerebellar Functional Severity Score (CCFS) | Through study completion, an average of 1 year | Correlations between primary outcomes and CCFS. | ClinicalTrials.gov |
| Secondary | SCA Functional Index | Through study completion, an average of 1 year | Correlations between primary outcomes and SCAFI. | ClinicalTrials.gov |
| Secondary | Friedreich Ataxia Rating Scale part II (FARS part II) | Through study completion, an average of 1 year | Correlations between primary outcomes and Activities of Daily Living from FARS part II. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Trail Making Test A | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)