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Trial · NCT04724720

Famotidine vs Placebo for the Treatment of Non-Hospitalized Adults With COVID-19

NCT04724720, Phase 2, Completed, Northwell Health

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Famotidine vs Placebo for the Treatment of Non-Hospitalized Adults With COVID-19. Trials, record NCT04724720. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04724720

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Famotidine vs Placebo for the Treatment of Non-Hospitalized Adults With COVID-19
NCT number
NCT04724720
Status
Completed
Phases
Phase 2
Enrollment
56 participants, actual
Lead sponsor
Northwell Health
Conditions
Covid-19
Interventions
Famotidine, Placebo
First posted
2021-01-26
Last updated
2026-06-15

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryNumber of Participants With Symptom ResolutionDay 28
Measured by the cumulative incidence of symptom resolution using the "COVID-19 Symptom Score" derived from the answers to a questionnaire based on the NIH endorsed guidelines and the recent FDA guidelines for studying COVID-19 in an outpatient setting. A shorter version has been utilized as a scoring system in the case series of famotidine use in non-hospitalized patients with COVID-19.
SecondaryTime to Symptom Resolution in DaysDay 28Assessed by modelling the resolution of cumulative symptoms over time using a mixed random effect model with co-variant adjustment.
SecondaryAssessment of Serious Adverse EventsDay 60Number of participants with treatment-related adverse events as assessed by CTCAE v4.0.
SecondaryChange in FerritinDay 7ferritin \[microg/L\]

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers9

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
3317057BACKGROUNDPubMed
32091533BACKGROUNDPubMed
32213337BACKGROUNDPubMed
32379955BACKGROUNDPubMed
32423584BACKGROUNDPubMed
32467561BACKGROUNDPubMed
32499303BACKGROUNDPubMed
32678530BACKGROUNDPubMed
32730238BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04724720

GET https://conductscience.org/api/trials/v1/NCT04724720/registered