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Trial · NCT04724837

Results by group46

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change in Urinary Albumin to Creatinine Ratio (UACR) From Baseline to Week 12Zibotentan 1.5 mg + Dapagliflozin0.48Standard Error 1.094milligram/gram (mg/g)
Change in Urinary Albumin to Creatinine Ratio (UACR) From Baseline to Week 12Placebo + Dapagliflozin0.72Standard Error 1.090milligram/gram (mg/g)
Change in UACR From Baseline to Week 12Zibotentan 0.25 mg + Dapagliflozin0.52Standard Error 1.106mg/g
Change in UACR From Baseline to Week 12Placebo + Dapagliflozin0.72Standard Error 1.090mg/g
Change in Office Systolic Blood Pressure From Baseline to Week 12Zibotentan 0.25 mg + Dapagliflozin-7.190% Confidence Interval -10.0 to -4.1Millimeters of mercury (mmHg)
Change in Office Systolic Blood Pressure From Baseline to Week 12Zibotentan 1.5 mg + Dapagliflozin-11.090% Confidence Interval -13.5 to -8.4Millimeters of mercury (mmHg)
Change in Office Systolic Blood Pressure From Baseline to Week 12Placebo + Dapagliflozin-3.490% Confidence Interval -5.8 to -1.0Millimeters of mercury (mmHg)
Change in Office Diastolic Blood Pressure From Baseline to Week 12Zibotentan 0.25 mg + Dapagliflozin-4.390% Confidence Interval -6.2 to -2.5mmHg
Change in Office Diastolic Blood Pressure From Baseline to Week 12Zibotentan 1.5 mg + Dapagliflozin-6.890% Confidence Interval -8.4 to -5.2mmHg
Change in Office Diastolic Blood Pressure From Baseline to Week 12Placebo + Dapagliflozin-1.490% Confidence Interval -2.9 to 0.1mmHg
Change in UACR From Baseline to Week 12Zibotentan 0.25 mg + Dapagliflozin0.52Standard Error 1.106mg/g
Change in UACR From Baseline to Week 12Zibotentan 1.5 mg + Dapagliflozin0.48Standard Error 1.094mg/g
Change in UACR From Baseline to Week 12Placebo + Dapagliflozin0.72Standard Error 1.090mg/g
Change in eGFR From Baseline to Week 1, Week 12, and Week 14Zibotentan 0.25 mg + DapagliflozinWeek 1-2.090% Confidence Interval -3.5 to -0.5milliliters/minutes/1.73 square metres
Change in eGFR From Baseline to Week 1, Week 12, and Week 14Zibotentan 1.5 mg + DapagliflozinWeek 1-3.990% Confidence Interval -5.2 to -2.6milliliters/minutes/1.73 square metres
Change in eGFR From Baseline to Week 1, Week 12, and Week 14Placebo + DapagliflozinWeek 1-3.190% Confidence Interval -4.4 to -1.8milliliters/minutes/1.73 square metres
Change in eGFR From Baseline to Week 1, Week 12, and Week 14Zibotentan 0.25 mg + DapagliflozinWeek 12-3.190% Confidence Interval -4.7 to -1.5milliliters/minutes/1.73 square metres
Change in eGFR From Baseline to Week 1, Week 12, and Week 14Zibotentan 1.5 mg + DapagliflozinWeek 12-3.090% Confidence Interval -4.4 to -1.6milliliters/minutes/1.73 square metres
Change in eGFR From Baseline to Week 1, Week 12, and Week 14Placebo + DapagliflozinWeek 12-1.990% Confidence Interval -3.3 to -0.6milliliters/minutes/1.73 square metres
Change in eGFR From Baseline to Week 1, Week 12, and Week 14Zibotentan 0.25 mg + DapagliflozinWeek 140.290% Confidence Interval -1.4 to 1.8milliliters/minutes/1.73 square metres

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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